Dr Alexandre Kabla

University of Cambridge

University departments: 
Department of Engineering

Position: Reader
Personal home page: http://kalab.emma.cam.ac.uk/
Email:   ajk61@cam.ac.uk

PubMed journal articles - click here

Dr Alexandre Kabla is pleased to consider applications from prospective PhD students.

Research description: 

My main research activities focus on the mechanical properties of soft disordered materials, including foams, granular materials, as well as biomaterials and living tissues. Current interests are fibrous networks rheology, embryo-morphogenesis and collective effects in cell populations.

Secondary Programme: 
Early Cancer Institute
Methods and technologies: 
Biosensor
Computational modelling
Imaging
Other
Tumour type interests: 
Brain and central nervous system
ajk61
Recent publications:
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Key publications: 

TPJ Wyatt, J Fouchard, et al., (2019), Actomyosin controls planarity and folding of epithelia in response to compression, Nature Materials, 1-9 2019.

N Srivastava, D Traynor, A Kabla, R Kay (2019), The Piezo channel is used by migrating cells to sense compressive load, to appear in PNAS, preprint on bioRxiv.

A Hallou, J Jennings, AJ Kabla (2017) Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination, Royal Society open science 4 (8), 161007

N Srivastava, RR Kay, AJ Kabla (2017), Method to study cell migration under uniaxial compression, Molecular biology of the cell 28 (6), 809-816

Andrew R. Harris, Loic Peter, Julien Bellis, Buzz Baum, Alexandre J. Kabla, and Guillaume T. Charras (2012), Characterizing the mechanics of cultured cell monolayers, PNAS 109:16449-16454.

Alexandre J. Kabla (2012), Collective Cell Migration: Leadership, Invasion and Segregation, J. R. Soc. Interface, 9:3268-3278.

Sri Ram Krishna Vedula, Man Chun Leong, Tan Lei Laic, Pascal Hersen, Alexandre J. Kabla, Chwee Teck Lim and Benoit Ladoux (2012), Emerging modes of collective cell migration induced by geometrical constraints, PNAS 109:12974-12979.

G.B. Blanchard, A.J. Kabla, N.L. Schultz, L.C. Butler, B. Sanson, N. Gorfinkiel, L. Mahadevan and R.J. Adams (2009), Tissue tectonics: morphogenetic strain rates, cell shape change and intercalation, Nature Methods 6, 458-464. D. Vader, A. J. Kabla, D.A. Weitz and L. Mahadevan (2009),

Strain-induced alignment in collagen gels, PLoS ONE 4(6): e5902. doi:10.1371/journal.pone.0005902.