I am a senior group leader at Cancer Research Technology Discovery Laboratories [CRTDL] (a wholly owned subsidiary of Cancer Research UK). CRTDL specialises in cancer drug discovery and in particular around drug discovery programs within industry-academic based alliances focusing on key biology themes within cancer. My own areas of research are within target validation and disease positioning which is the group I lead. Alongside a general expertise in cancer biology and drug discovery my specialism?s focus around cancer metabolism, cancer epigenetics and cell signalling.