Search results
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Dr Catherine Lindon
... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...
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Dr Athena Matakidou
... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...
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Dr Mariann Bienz
... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...
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Dr Dario Bressan
... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...
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Dr Frank McCaughan
My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...
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Professor Gillian Murphy
... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...
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Dr James Nathan
Cellular mechanisms of oxygen and metabolite sensing: ...
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Dr James Rudd
... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...
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Ms Paola Marco
... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...
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Dr Marisa Segal
... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...
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Dr Adrien Hallou
Initially trained as a physicist and a chemist at the Ecole Normale Supérieure (Paris, France), I developed my interest for quantitative approaches of biological systems during my MPhil and PhD in Biophysics at the University of Cambridge. I am now a...
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Dr Ahsan MEMON
Ahsan has developed a sui generis versatile holographic system capable of diverse photo-perturbation techniques including photo-manipulation, photo-activation, photo-ablation, optical-trapping and optogenetics, combined with multi-modal imaging...
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Dr Aisling Redmond
Aisling received her undergraduate degree in Genetics from Trinity College Dublin and PhD from Dublin City University. She completed postdoctoral fellowships in the breast cancer field at the Royal College of Surgeons in Ireland and Cancer Research UK...
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Professor Alan Warren
Our long-term goal is to elucidate the molecular mechanisms of ribosome assembly in eukaryotic cells and to understand how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome,...
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Dr Alexey Larionov
Hormonal treatment and resistance in Breast cancer Heritable cancer predisposition NGS data analysis
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Dr Annalisa Mupo
Acute myeloid leukemia (AML) is a molecularly diverse malignancy representing 15-20% of all childhood and around 35% of all adult leukemias. My work aims to study commonly occurring mutations in AML-NK (normal karyotype) using sophisticated mouse models.
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Dr Anna Piskorz
I’m a molecular biologist focus on translational research in high grade serous ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better...
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Professor Tony Green
Tony Green is Professor of Haemato-oncology in the University of Cambridge and honorary Consultant Haematologist at Addenbrookes Hospital. He was appointed Head of the University Department of Haematology (2000-2020), and in 2016 was appointed Director...
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Dr Alex Samoshkin
I have been a Translational Technology Manager in the University of Cambridge since 2017. My primary role is to connect researchers in technology/physical sciences with clinicians and academics to develop new collaborative translational projects. I...
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Professor Ben Simons
We are interested in the role of stem cells in the maintenance of adult tissue. In particular, by drawing of the results of inducible genetic labelling, we have studied the mechanism of epidermal maintenance in mouse. Currently, we are extending these...
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Miss Ariella Stewart
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Dr Anne Warren
Responsible for providing histopathological support and tissue sampling and assessment for research projects of the urological malignancies research programme.
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Dr Cinzia Esposito
Hypoxia signalling
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Dr Christine Farr
I am interested in chromosome biology and the relationship between the structural organisation of vertebrate chromosomes and their function. Previously we have derived a minimal human chromosome, studied de novo telomere formation and genetically...
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Mr Calvin Cheah
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Ms Danya Cheeseman
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Dr Dominick McIntyre
Head of the CRUK CI Imaging Core Facility, specialising in preclinical MRI and image databases, and running a team supporting research in clinical & preclinical MR, BLI/FLI, CT and radionuclide imaging, and ultrasound.
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Dr Shiqing Mao
DNA modifications
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Dr Elisa Laurenti
Daily blood cell production is guaranteed throughout life by a hierarchy with haematopoietic stem cells (HSC) at its root. HSC are very different from other haematopoietic cell types and have unique functional properties, such as their infrequent...
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Professor Andrew Flewitt
I work in large area electronics and MEMS devices, with a particular focus on acoustic wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic pumps without...
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Dr Andrew Bannister
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes ...
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Dr Simon Cook
In terms of basic science we are interested in how protein kinase and lipid signalling pathways control cell fate decisions such as proliferation versus differentiation and survival versus death. However, these pathways are frequently de-regulated in...
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Dr David Adams
David performs forward genetic screens to uncover cancer genes and pathways and leads a programme to decode the genomes of several mouse strains. He also leads the Mouse Genomes Project and the Mouse Genetics Project. The Mouse Genomes Project is...
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Professor Eric Miska
Our main goal is to understand how cells interpret genetic and epigenetic information as well as environmental cues to determine their correct cell fate, i.e. to make the decision to divide, die or differentiate. The recent discovery of a large...
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Professor Evis Sala
Now based in Rome, my research in Cambridge focused on integrated diagnostics, through the clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and metabolic tumour habitat imaging...
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Dr Helen Morris
In the Primary Care Unit I've managed and collaborated on a number of randomised controlled trials and other well-designed studies in the field of cancer and genetics in a primary care setting: 1) The GRAIDS (Genetic Risk Assessment on the Internet and...
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Professor Heike Laman
F-box proteins (FBPs) are the substrate-recruiting subunits of SCF (Skp1-cullin1-FBP)-type E3 ubiquitin ligases, but ubiquitinated substrates have been identified for only a few of the sixty-nine FBPs identified in humans. The major aim of my laboratory...
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Dr Roy Rabbie
We use DNA sequencing of patients and their tumours to study genomic evolution in melanoma.
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Dr John Lizhe Zhuang
... that initiate BO and OAC. Firstly, I have established a series of patient derided organoid models from normal tissues, BO, and OAC, and ...
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Professor Ming-Qing Du
... and molecular investigations. We have been undertaking a series of research programmes to elucidate the pathology, immunophenotype, and ...
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Dr David Fairen-Jimenez
Our research concerns the study of the molecular mechanisms that control adsorption processes in porous materials. We are particularly interested in drug delivery systems, where nanotechnology has a fundamental impact to revolutionise cancer diagnosis...
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Miss Jamie McGinn
Project title: Epithelial cell dynamics during postnatal growth; relevance for ...
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Mr Arqum Anwar
Rotation Project: The project aims to investigate the cellular role(s) of a novel factor expected to be involved in DNA damage response. Specifically, the interactome of the protein will be explored using co-immunoprecipitation followed by mass...
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Dr Anny Wong
... treatment and investigations. She also specialises in the follow-up care of children who have finished their cancer treatment. ...
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Professor Kevin Brindle
Magnetic resonance imaging (MRI) is a well-established, clinically applicable, tool for determining tissue morphology. The techniques of molecular imaging seek, through the use of appropriate probe molecules, to transfer into the MR image of tissue...
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Professor Charlotte Coles
... radiotherapy in patients at low risk of recurrence – in follow up: 2018 patients recruited; 71 UK centres 2. IMPORT HIGH : phase ... IMRT for patients at higher risk of recurrence - in follow up: 2617 patients recruited; 77 UK centres 3. PRIMETIME : ...
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Mrs Eva Serrao
... formed alanine and lactate as a probe to detect, grade and follow progression of precursor lesions of pancreatic cancer before any ...
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Miss Nicola Fearnhead
Miss Nicola Fearnhead has been a Consultant Colorectal Surgeon at Addenbrooke's Hospital, Cambridge since 2006. She is a graduate of Pembroke College, Cambridge and Merton College, Oxford where she was a Rhodes Scholar. Surgical training was...
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Dr George Follows
My laboratory research focuses on transcriptional regulation and chromatin structure. I maintain a supervisory role for a research assistant in Professor Green's laboratory, CIMR, funded through a personal LRF project grant. I have now taken a clinical...
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Dr Hannah Harrison
... risk-stratification for kidney cancer screening and follow-up. Her most rencet project, funded by CRUK, is investigating ...
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Professor Julie Ahringer
We investigate the functions chromatin regulatory complexes implicated in human disease using the C. elegans model system. These include the histone deacetylase complex NuRD, the Retinoblastoma complex DRM, and a TIP60 histone acetyltransferase complex....
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Dr John Suckling
Our research programme leverages two decades of advancements in magnetic resonance imaging and assocaited methodologies to accrue the evidence to inform the difficult discussions with patients with brain tumours, and their families, on the balance...