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  1. Dr Catherine Lindon

    ... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...

  2. Dr Athena Matakidou

    ... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...

  3. Dr Mariann Bienz

    ... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...

  4. Dr Dario Bressan

    ... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...

  5. Dr Frank McCaughan

    My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...

  6. Professor Gillian Murphy

    ... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...

  7. Dr James Nathan

    Cellular mechanisms of oxygen and metabolite sensing: ...

  8. Dr James Rudd

    ... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...

  9. Ms Paola Marco

    ... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...

  10. Dr Marisa Segal

    ... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...

  11. Dr Adrien Hallou

    Initially trained as a physicist and a chemist at the Ecole Normale Supérieure (Paris, France), I developed my interest for quantitative approaches of biological systems during my MPhil and PhD in Biophysics at the University of Cambridge. I am now a...

  12. Dr Ahsan MEMON

    Ahsan has developed a sui generis versatile holographic system capable of diverse photo-perturbation techniques including photo-manipulation, photo-activation, photo-ablation, optical-trapping and optogenetics, combined with multi-modal imaging...

  13. Dr Aisling Redmond

    Aisling received her undergraduate degree in Genetics from Trinity College Dublin and PhD from Dublin City University. She completed postdoctoral fellowships in the breast cancer field at the Royal College of Surgeons in Ireland and Cancer Research UK...

  14. Professor Alan Warren

    Our long-term goal is to elucidate the molecular mechanisms of ribosome assembly in eukaryotic cells and to understand how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome,...

  15. Dr Alexey Larionov

    Hormonal treatment and resistance in Breast cancer Heritable cancer predisposition NGS data analysis

  16. Dr Annalisa Mupo

    Acute myeloid leukemia (AML) is a molecularly diverse malignancy representing 15-20% of all childhood and around 35% of all adult leukemias. My work aims to study commonly occurring mutations in AML-NK (normal karyotype) using sophisticated mouse models.

  17. Dr Anna Piskorz

    I’m a molecular biologist focus on translational research in high grade serous ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better...

  18. Professor Tony Green

    Tony Green is Professor of Haemato-oncology in the University of Cambridge and honorary Consultant Haematologist at Addenbrookes Hospital. He was appointed Head of the University Department of Haematology (2000-2020), and in 2016 was appointed Director...

  19. Dr Alex Samoshkin

    I have been a Translational Technology Manager in the University of Cambridge since 2017. My primary role is to connect researchers in technology/physical sciences with clinicians and academics to develop new collaborative translational projects. I...

  20. Professor Ben Simons

    We are interested in the role of stem cells in the maintenance of adult tissue. In particular, by drawing of the results of inducible genetic labelling, we have studied the mechanism of epidermal maintenance in mouse. Currently, we are extending these...

  21. Mr Adam Palmer

  22. Mrs Angela Godoy

  23. Dr Adrian Kelly

    Biology of MHC class I and class II antigen processing and presentation pathways.

  24. Dr Chiwen Chang

    1. Interaction between NK cells and HLA Class I antigen during immune response. 2. Immunotherapy for cancers and autoimmune diseases.

  25. Dr Christopher Shepherd

  26. Professor Charlotte Coles

    Charlotte Coles is Professor of Breast Cancer Clinical Oncology and NIHR Research Professor at the CRUK Cambridge Centre. Her research aims are to provide breast cancer patients with the best chance of cure with least side effects by personalising...

  27. Professor David Rubinsztein

  28. Dr Elizabeth Soilleux

  29. Professor Andrew Flewitt

    I work in large area electronics and MEMS devices, with a particular focus on acoustic wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic pumps without...

  30. Dr Andrew Bannister

    I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes ...

  31. Dr Simon Cook

    In terms of basic science we are interested in how protein kinase and lipid signalling pathways control cell fate decisions such as proliferation versus differentiation and survival versus death. However, these pathways are frequently de-regulated in...

  32. Dr David Adams

    David performs forward genetic screens to uncover cancer genes and pathways and leads a programme to decode the genomes of several mouse strains. He also leads the Mouse Genomes Project and the Mouse Genetics Project. The Mouse Genomes Project is...

  33. Professor Eric Miska

    Our main goal is to understand how cells interpret genetic and epigenetic information as well as environmental cues to determine their correct cell fate, i.e. to make the decision to divide, die or differentiate. The recent discovery of a large...

  34. Professor Evis Sala

    Now based in Rome, my research in Cambridge focused on integrated diagnostics, through the clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and metabolic tumour habitat imaging...

  35. Dr Helen Morris

    In the Primary Care Unit I've managed and collaborated on a number of randomised controlled trials and other well-designed studies in the field of cancer and genetics in a primary care setting: 1) The GRAIDS (Genetic Risk Assessment on the Internet and...

  36. Professor Heike Laman

    F-box proteins (FBPs) are the substrate-recruiting subunits of SCF (Skp1-cullin1-FBP)-type E3 ubiquitin ligases, but ubiquitinated substrates have been identified for only a few of the sixty-nine FBPs identified in humans. The major aim of my laboratory...

  37. Mr James Watson

  38. Mrs Sarah Fesco

  39. Professor Andrea Brand

  40. Mr Arqum Anwar

    ... by mass spectrometry. The data will be used, along with KO cell lines and ChIP-seq experiments, to delineate the function(s) of the ...

  41. Dr Ashwin Seshia

    One of the research thrusts in my group is the development of microelectromechanical and microfluidics based platforms for early diagnosis. We also research microfabricated biophysical tools to characterise biological systems at the molecular, cellular...

  42. Dr Alvis Brazma

    ... (microarray, sequencing) data analysis. Data integration. Cell cycle. I am in charge of running and developing the transcriptomics data ...

  43. Dr Alejandra Bruna

    ... the effects of the TGF-beta pathway in breast cancer stem cell (BCSC) regulation. To define a role of the TGF-beta pathway in the ... of human BCSCs, we have analyzed a panel of breast cancer cell lines that represent the molecular heterogeneity present in primary ...

  44. Dr Adeeba Fathima Valiya Thodiyil

    Single cell/Tissue imaging, quantitative microscopy, image analysis  ...

  45. Professor Adrian Liston

    We are focussed on understanding the biology of regulatory T cells within the tissues. How they migrate there, what controls their numbers and their functions, both immunological and tissue homeostatic in nature. Our approach is to identify key unknowns...

  46. Professor Anna Philpott

    ... therapies in cancer, particularly of neurological origin, and for regerenative medicine. Our work in the nervous system is ...

  47. Professor Anthony Davenport

    Our research group focuses on understanding the role of G-protein-coupled receptors (GPCRs, targets for about ~50% of current drugs) together with their transmitters in humans. We use in vitro pharmacology and in vivo imaging using positron emission...

  48. Professor Carlos Caldas

    ... that suggests that different cancers have different cells of origin. The identification and characterisation of these cancer stem cells and ...

  49. Dr Daniel Munoz-Espin

    ... and the fundamental processes and mechanisms that lie at the origin of cancer. We are also developing novel tools and nanodevices for cancer ...

  50. Professor Elizabeth Murchison

    Elizabeth Murchison studies the genetics and evolution of clonally transmissible cancers. Transmissible cancers are unusual cancers that have survived beyond the bodies of their original hosts via the transmission of living cancer cells. Naturally...

  51. Dr John Lizhe Zhuang

    ... risks of malignant progression. Understanding the cell of origin of these lesions and the drivers of malignant progression is crucial for ... I seek to answer bigger questions regarding the cell origin of cancer and its precancerous lesions, its evolutionary trajectory, and ...

  52. Professor Richard Gilbertson

    Professor Richard Gilbertson FRS FMedSci FRCP is a paediatric oncology clinician scientist and a Senior Group Leader at the Cancer Research UK Cambridge Institute, University of Cambridge. He is the Li Ka Shing Chair of Oncology, Head of the Dept of...

  53. Dr Sara Pensa

    ... breast cancer and if this is also affected by the cellular origin of tumours. ...

  54. Professor Walid Khaled

    ... and development. In particular, we focus on how the cell of origin affects the differentiation trajectory of nascent tumour cells and ...

  55. Dr Ali Amin Al Olama

    ... research has focused on discovery of genetic risk factors of prostate cancer through genome-wide association studies and fine-mapping. I am a core member of an international consortium PRACTICAL (Prostate Cancer Association Group to Investigate Cancer Associated Alterations ...

  56. Professor Antonis Antoniou

    ... of risk prediction models for familial breast, ovarian, prostate and other cancers with a familial component; - the identification and ...

  57. Dr Alison Dunning

    ... international consortia for breast, ovarian, endometrial and prostate cancer association studies: BCAC http://bcac.ccge.medschl.cam.ac.uk, ...

  58. Dr Antony Rix

    ... announced a substantial investment led by XTX Ventures and Prostate Cancer Research - for more details see https://lucidamedical.com/2021-cambridge-ai-startup-prostate-cancer-investment/ ...

  59. Dr Claire Crafter

    My main focus is on understanding the mechanism of action of a range of agents targetting the PI3 Kinase pathway, particularly the AKT inhibitor AZD5363 and the mTORC1/2 inhibitor, AZD2014. I also have a stong interest in combination screening and...

  60. Ms Ceilidh Welsh

    ... recruited across radiotherapy trials in Breast Cancer, Prostate Cancer and Head & Neck Cancer. ...

  61. Dr Danish Mazhar

    ... awarded a PhD by Imperial College London for his research in Prostate Cancer. He has also previously received the McElwain Prize from the ... is the Principal Investigator of numerous clinical trials in Prostate, Bladder and Testis Cancers. He is a member of National Cancer ...

  62. Mr David Thurtle

    ... laparoscopic prostatectomy. Early detection of prostate cancer. Risk Prediction in prostate cancer ...

  63. Professor Douglas Easton

    ... to cancer, with particular emphasis on breast and prostate cancer. I also have particular interests in the genetic epidemiology ... conducting association studies in breast (BCAC) and prostate cancer (PRACTICAL), and in BRCA1/2 carriers. ...

  64. Professor David Neal

    ... in CRI with interest in androgen receptor signalling in prostate cancer. We are studying androgen regulated genes as mediators of ... experimental medicine approaches in patients with high risk prostate cancer. I am also PI on a collaborative study of sequencing for human ...

  65. Dr Andreas Bender

    ... large amounts of chemical or biological data related to cancer drug discovery you are very welcome to contact me to see in which way I ...

  66. Dr Ashray Gunjur

    ... broadly interested in immuno-oncology and the link between cancer and the gut microbiome, and am undertaking a PhD supervised by Dr David ... between gut microbiota and outcomes in patients with rare cancer types. ...

  67. Dr Alasdair Russell

    ... to complex, patient-relevant model systems in a pre-clinical setting. Further, we use these novel models in a range of pre-clinical trials to advance our understanding of disease. ...

  68. Mr Aman Coonar

    Clinical research in thoracic cancer with emphasis on surgery. Local PI for PULMICC study- a RCT of metastectomy v best other care for colorectal metastases to lung.

  69. Mr Amit Roshan

    ... CRUK / Royal College of Surgeons Clinician Scientist with a clinical interest in early stage melanoma. My research focus is currently ...

  70. Dr Amos Burke

    ... a member of the National Cancer Research Institute Lymphoma Clinical Studies Group and chairs its paediatric Non-Hodgkin Lymphoma subgroup. ... laboratory collaborations and currently co-supervises a Clinical and a basic science PhD student. At a national level Dr Burke is the ...

  71. Dr Andrew Pierce

    DNA damage and repair, oncology clinical biomarkers ...

  72. Dr Andrew Gee

    Since 1995, I have been working on technical aspects of clinical ultrasonic imaging, with particular emphasis on three-dimensional ...

  73. Mr Angelos Kolias

    Angelos Kolias is a Clinical Senior Lecturer and Consultant Neurosurgeon in the Department of Clinical Neurosciences, Addenbrooke’s Hospital and University of Cambridge, ... Neurology and Neurosurgery, Queen Square, London. His clinical interests include surgery for brain tumours (special interest in skull ...

  74. Dr Geoff Macintyre

    ... HGSOC samples with a specific focus on modelling tumour heterogeneity and subclonal tumour evolution. ...

  75. Professor Grant Stewart

    Professor Stewart is an academic surgeon at the University of Cambridge, with a focus on developing and promoting surgery related clinical trials and translational research. Grant has a specific interest in optimising management of patients with...

  76. Dr Hanna Najgebauer

    ... models based on their clinical relevance and covered genomic heterogeneity observed in primary disease. ...

  77. Dr Joo-Hyeon Lee

    ... regeneration. We are also interested in defining cellular heterogeneity and plasticity during this process. Elucidating the normal ...

  78. Dr Lucy Yates

    ... to uncover the genomic basis of breast cancer, intra-tumour heterogeneity and the evolutionary patterns underlying metastasis. My current ...

  79. Professor Paul Pharoah

    ... how germline genetic variation influences disease heterogeneity and heterogeneity in the clinical outcomes of cancer. ...

  80. Mr Richard Mair

    ... this interaction. I am interested in understanding the heterogeneity present within glioblastoma and how this can be understood ...

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