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  1. Dr Catherine Lindon

    ... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...

  2. Dr Athena Matakidou

    ... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...

  3. Dr Mariann Bienz

    ... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...

  4. Dr Dario Bressan

    ... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...

  5. Dr Frank McCaughan

    My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...

  6. Professor Gillian Murphy

    ... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...

  7. Dr James Nathan

    Cellular mechanisms of oxygen and metabolite sensing: ...

  8. Dr James Rudd

    ... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...

  9. Ms Paola Marco

    ... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...

  10. Dr Marisa Segal

    ... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...

  11. Dr David Gilligan

    David Gilligan is a Consultant Clinical Oncologist at Addenbrooke's and Papworth Hospitals in Cambridge. He is the Clinical Lead for Acute Oncology at Addenbrooke's. He trained in pre clinical medicine at the University of Edinburgh and clinical...

  12. Mr David Thurtle

    Radiological assessment of prostatic osseous metastases. Robotic-assisted laparoscopic prostatectomy. Early detection of prostate cancer. Risk Prediction in prostate cancer

  13. Professor David Glover

    Our laboratory studies the regulation of progression through mitosis and meiosis in animal cells. The high degree of evolutionary conservation of these regulatory mechanisms means that findings in model organisms are readily applicable to human cells....

  14. Dr Roisin Owens

    Our group works on integrating biological models with electronic devices to generate systems that can be predictive of real biological systems, for drug discovery and therapeutics. We combine expertise in a wide range of disciplines including...

  15. Mr Thierry Lefebvre

    Radiotherapy is often prescribed in oncology clinics to treat solid tumours and to limit the development and the propagation of cancer cells. The lack of oxygenation seen in some tumour regions under chaotic and unrestricted cellular growth constitute a...

  16. Professor Walid Khaled

    My laboratory works on defining the early cellular and molecular events that drive tumour initiation and development. In particular, we focus on how the cell of origin affects the differentiation trajectory of nascent tumour cells and dictates changes...

  17. Dr Andrej Alendar

    RNA methyltransferases

  18. Mr Alexander Evtushenko

  19. Dr Andrew King

  20. Dr Anna Piskorz

    I’m a molecular biologist focus on translational research in high grade serous ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better...

  21. Dr Basma Greef

    Supervisor Prof Margaret Ashcroft. Disruption of hypoxia response pathways in renal cancer and how these can be harnessed to develop new treatments. My other interests include clinical trials and the effective management of toxicities related to widely...

  22. Dr Cedric Ghevaert

    Cedric Gevaert graduated from the medical school of the University Libre de Bruxelles in 1997 and subsequently became a fellow of the Royal College of Physicians, London (2000). He specialised in Haematology and became a fellow of the Royal College of...

  23. Dr Christian Dillon

  24. Dr Joanna Baxter

    The Cambridge Blood and Stem Cell Biobank is a facility of over 6000 viable and nucleic acid samples, the majority from patients with haematological malignancy and clonal blood cell disorders; and the remainder, around 20%, from normal individuals,...

  25. Miss Ee June Chua

  26. Dr Elham Shirazi

  27. Professor Duncan Jodrell

    I endeavour to integrate and optimise the pre-clinical development and science-led clinical application of novel therapies and novel therapeutic combinations, including first into man (phase I) and associated studies.  My research goal is to identify...

  28. Dr Kathryn Chapman

    Kathryn Chapman is the Deputy Director of the Milner Therapeutics Institute, a dynamic partnership between pharmaceutical companies and academics at the University of Cambridge and associated Institutes. Its mission is to connect the intellectual know...

  29. Professor Vincent Gnanapragasam

    Vincent J Gnanapragasam holds a personal Chair in Urology at the University of Cambridge and is an Honorary Consultant Urologist at Addenbrooke’s Hospital, Cambridge. He graduated from Newcastle University and following basic surgical training, was...

  30. Mr Arqum Anwar

    ... role(s) of a novel factor expected to be involved in DNA damage response. Specifically, the interactome of the protein will be ...

  31. Mr Amit Roshan

    ... is currently exploring the utility of circulating tumour DNA (ctDNA) in early melanoma, and progressing our understanding of disease ...

  32. Dr Andrew Pierce

    DNA damage and repair, oncology clinical biomarkers

  33. Dr Emma Beddowes

    Investigating the development and application of circulating free nucleic acids to breast cancer research.

  34. Dr Christine Farr

    I am interested in chromosome biology and the relationship between the structural organisation of vertebrate chromosomes and their function. Previously we have derived a minimal human chromosome, studied de novo telomere formation and genetically...

  35. Dr Claudia Ribeiro de Almeida

    ... and do so by employing hazardous mechanisms of somatic DNA mutation and DNA deletion-recombination with remarkable efficiency. Increasing evidence ...

  36. Professor Douglas Easton

    My main research area is genetic susceptibility to cancer, with particular emphasis on breast and prostate cancer. I also have particular interests in the genetic epidemiology of BRCA1 and BRCA2, intermediate markers of cancer risk (such as breast...

  37. Dr Shiqing Mao

    DNA modifications

  38. Dr Fazlur Rahman Talukdar

    ... research initiative focused on developing circulating tumour DNA (ctDNA) based biomarkers derived from minimally invasive biospecimens, with ... in 2015. During this tenure, my research aimed to identify DNA methylome alterations linked to esophageal cancer within high-incidence ...

  39. Miss Nicola Fearnhead

    ... pelvic floor disorders including rectovaginal fistula repair, intestinal failure and functional bowel disorders. Research ...

  40. Dr Joo-Hyeon Lee

    ... translation, and cellular dynamics in homeostasis and injury repair. We investigate the regulatory networks that need to be turned on and ...

  41. Dr Kate Dry

    DNA repair and DNA damage signalling The main focus of research in our lab is to ... cells detect DNA damage and signal its presence to the DNA repair, transcription and cell cycle machineries. We believe that a deeper ...

  42. Dr Kerstin Meyer

    ... for biological processes related to cancer, such as DNA repair and are collaborating with Zvi Livneh and Tamar Paz-Elizur to carry out epidemiologic studies into the role of DNA repair in lung cancer predisposition. ...

  43. Dr Lori Passmore

    We use a hybrid approach to study the structure and function of multi-protein complexes. A major focus of the lab is on complexes involved in the regulation of mRNA polyadenylation and deadenylation. Eukaryotic genes are normally transcribed as pre...

  44. Dr Luca Pellegrini

    ... requires the accurate replication of the genome and the repair of any DNA lesion that might block replication or alter the encoded ...

  45. Dr Michael Boemo

    My group develops new computational methods to study how dysregulation and errors in DNA replication and mitosis lead to genome instability. We use and develop cutting-edge methodologies from machine learning, bioinformatics, software engineering, high...

  46. Dr Sumru Bayin

    ... how complex organs like the brain are generated or undergo repair. The neonatal mouse cerebellum has emerged as a powerful model system to ... neonatal cerebellum and identify factors that could enhance repair.  We have previously shown that the cerebellum can recover from the ...

  47. Dr Phil Jones

    ... mode once more. This behavioural plasticity allows tissue repair without the need for 'reserve' stem cells. The ability of progenitors to produce excess progenitor daughters for wound repair represents a potential vulnerability. Mutations may bias progenitor ...

  48. Dr Finian Leeper

    ... of thiamin diphosphate (TPP) analogues for inhibition, mechanistic and crystallographic studies on TPP-dependent enzymes. ...

  49. Dr Luigi Aloj

    ... from basic preclinical radiopharmaceutical development and mechanistic studies, to novel clinical applications in nuclear medicine ...

  50. Professor Margaret Ashcroft

    Our research focuses on understanding the molecular mechanisms regulating the cellular response to low oxygen (hypoxia). Hypoxia is a key feature associated with the pathology of many diseases, including cancer. ...

  51. Dr Ritwick Sawarkar

    ... and mouse genetic models. We aim to gain novel insights and mechanistic understanding of transcriptional response to stress and toxins. ...

  52. Dr Alex Cagan

    ... the power of comparative evolutionary genomics to gain insights into somatic mutational processes across the tree of life. ...

  53. Dr David Fairen-Jimenez

    ... we can recognise these relationships and discover hidden insights, extrapolating the behaviour towards optimal systems. Once an optimal ...

  54. Dr Fazal Hadi

    ... Jason Carroll's lab and AstraZeneca working to get further insights into mechanism of action of selective estrogen receptor degraders. ...

  55. Professor Fiona Gilbert

    ... in new techniques which offer more accurate diagnosis or new insights into the tumour microenvironment. My experience with the health ...

  56. Professor Jasmin Fisher

    ... formal methods can be beneficial for gaining new biological insights and directing new experimental avenues. Once an executable model has ...

  57. Mr Kourosh Saeb-Parsy

    ... genetic mutation in normal human tissue and the associated insights into oncogenesis. www.saeb-parsy.group.cam.ac.uk ...

  58. Dr Kelly Fagan Robinson

    ... programmes, which in turn has fostered development of insights into communication of risks and prevention of infectious diseases, as ...

  59. Dr Kyren Lazarus

    My overall career ambition is to develop novel insights into breast cancer pathology to help improve clinical outcomes for ...

  60. Dr John Lizhe Zhuang

    ... allowing us to map an evolutionary trajectory and giving insights of how clones are selected in cancer initiation and development. It is ...

  61. Dr Alasdair Russell

    Alasdair heads up a specialised team that provide a centralised ‘Hub’ for the innovation and application of state-of-the-art Genome Editing technologies to complex, patient-relevant model systems in a pre-clinical setting. Further, we use these novel...

  62. Dr Andrew Bannister

    ... to use the knowledge gained to develop novel anti-cancer therapeutic compounds. ...

  63. Professor Anna Philpott

    ... that are disrupted in tumorigenesis and point the way to new therapeutic interventions. ...

  64. Professor Kevin Brindle

    Magnetic resonance imaging (MRI) is a well-established, clinically applicable, tool for determining tissue morphology. The techniques of molecular imaging seek, through the use of appropriate probe molecules, to transfer into the MR image of tissue...

  65. Dr Bristi Basu

    ... candidate agents into early phase clinical trials of novel therapeutic drugs as chief investigator, principal investigator and ...

  66. Professor Carlos Caldas

    ... validate prognostic and predictive signatures and therapeutic targets with the aim of clinical application. ...

  67. Dr Simon Cook

    ... they control. This makes them attractive targets for therapeutic intervention and new drugs that target these pathways are in ...

  68. Dr Pippa Corrie

    My research is based on improving outcomes for patients with chemoresistant cancers. I am chief investigator of the national adjuvant melanoma phase 3 trial, collaborating with Mark Middleton, Oxford, who leads associated translational studies focusing...

  69. Mr Daniel Kottmann

    ... project focuses on the identification and validation of new therapeutic targets for squamous cell lung cancer. ...

  70. Dr Ahsan MEMON

    ... cellular and molecular behaviour. As one of its first applications, this holographic system was deployed to the study of cancer and ...

  71. Dr Adrian Ionescu

    ... spintronic devices are used as bio-assays in life science applications. ...

  72. Professor Andrew Flewitt

    ... wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make ...

  73. Dr Arnaud Comment

    ... spectroscopy and imaging in particular for biomedical applications. My research is focused on three main axes: Methodology in DNP, ... and test of in vivo and in vitro protocols for biomedical applications. Real-time uptake and metabolism, in particular in vivo studies ...

  74. Professor Carola-Bibiane Schönlieb

    ... segmentation and object tracking - Large scale computing - Applications in processing of photographs, biomedical imaging (MRI, PET/SPECT, ...

  75. Professor Chris Rodgers

    ... metabolic imaging and phosphorus metabolic imaging for applications in the brain, heart and liver. I am Coordinator of the UK7T ...

  76. Mr David Chalmers

    ... Institute. We create and support software services and applications for the Research Groups, Core Facilities and Operations ...

  77. Dr Daniel Popa

    Development of ultrafast fiber laser systems for medical applications, including surgery and imaging, such as coherent Raman microscopy. ...

  78. Dr Iosif Mendichovszky

    ... pharmaceuticals to clinical practice and innovative clinical applications of current radiotracers. My research is focused on hybrid imaging ...

  79. Dr Ali Amin Al Olama

    ... has focused on discovery of genetic risk factors of prostate cancer through genome-wide association studies and fine-mapping. I am a core member of an international consortium PRACTICAL (Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the ...

  80. Dr Andreas Bender

    ... large amounts of chemical or biological data related to cancer drug discovery you are very welcome to contact me to see in which way I ...

  81. Dr Alejandra Bruna

    ... aimed to study the effects of the TGF-beta pathway in breast cancer stem cell (BCSC) regulation. To define a role of the TGF-beta pathway in ... of human BCSCs, we have analyzed a panel of breast cancer cell lines that represent the molecular heterogeneity present in primary ...

  82. Professor Antonis Antoniou

    ... component; - the identification and characterisation of cancer risks for genetically susceptible individuals, such as those carrying ...

  83. Dr Alison Dunning

    Work in the Centre for Cancer Genetic Epidemiology "wet lab" involves running very high throughput ... (NGS) studies. We search for genetic risk factors for both cancer susceptibility and treatment-response. In this we collaborate closely ... consortia for breast, ovarian, endometrial and prostate cancer association studies: BCAC http://bcac.ccge.medschl.cam.ac.uk, CIMBA ...

  84. Dr Ashray Gunjur

    ... broadly interested in immuno-oncology and the link between cancer and the gut microbiome, and am undertaking a PhD supervised by Dr David ... between gut microbiota and outcomes in patients with rare cancer types. ...

  85. Dr Aisling Redmond

    ... She completed postdoctoral fellowships in the breast cancer field at the Royal College of Surgeons in Ireland and Cancer Research UK Cambridge Institute (with Professor Jason Carroll), ...

  86. Professor Alan Warren

    ... how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome, containing ... it is also important for oncogenesis: a novel class of human cancer predisposition disorder has recently emerged that is caused by mutations ...

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