Error message

The page you requested does not exist. For your convenience, a search was performed using the query events thu 19 may 0930 cancer resistance naked mole rat tale transformation.

Search results

  1. Dr Catherine Lindon

    ... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...

  2. Dr Athena Matakidou

    ... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...

  3. Dr Mariann Bienz

    ... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...

  4. Dr Dario Bressan

    ... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...

  5. Dr Frank McCaughan

    My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...

  6. Professor Gillian Murphy

    ... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...

  7. Dr James Nathan

    Cellular mechanisms of oxygen and metabolite sensing: ...

  8. Dr James Rudd

    ... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...

  9. Ms Paola Marco

    ... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...

  10. Dr Marisa Segal

    ... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...

  11. Dr David Gilligan

    David Gilligan is a Consultant Clinical Oncologist at Addenbrooke's and Papworth Hospitals in Cambridge. He is the Clinical Lead for Acute Oncology at Addenbrooke's. He trained in pre clinical medicine at the University of Edinburgh and clinical...

  12. Mr David Thurtle

    Radiological assessment of prostatic osseous metastases. Robotic-assisted laparoscopic prostatectomy. Early detection of prostate cancer. Risk Prediction in prostate cancer

  13. Professor David Glover

    Our laboratory studies the regulation of progression through mitosis and meiosis in animal cells. The high degree of evolutionary conservation of these regulatory mechanisms means that findings in model organisms are readily applicable to human cells....

  14. Dr Roisin Owens

    Our group works on integrating biological models with electronic devices to generate systems that can be predictive of real biological systems, for drug discovery and therapeutics. We combine expertise in a wide range of disciplines including...

  15. Mr Thierry Lefebvre

    Radiotherapy is often prescribed in oncology clinics to treat solid tumours and to limit the development and the propagation of cancer cells. The lack of oxygenation seen in some tumour regions under chaotic and unrestricted cellular growth constitute a...

  16. Professor Walid Khaled

    My laboratory works on defining the early cellular and molecular events that drive tumour initiation and development. In particular, we focus on how the cell of origin affects the differentiation trajectory of nascent tumour cells and dictates changes...

  17. Dr Adrian Ionescu

    I currently work as a post-doctoral research associate at the Cavendish Laboratory, Department of Physics, University of Cambridge, in the Thin Film Magnetism (TFM) group with Prof. Crispin Barnes on an ERC International Training Network project,...

  18. Dr Alessandro Ruggiero

  19. Dr Andrew Gee

    Since 1995, I have been working on technical aspects of clinical ultrasonic imaging, with particular emphasis on three-dimensional imaging and elastography (stiffness imaging). Along with Richard Prager and Graham Treece, I lead the Medical Imaging...

  20. Mr Angelos Kolias

    ... on Acquired Brain and Spine Injury. During the COVID-19 pandemic, he is leading the neurosurgical theme of the  CovidSurg ...

  21. Mr Asif Jah

    Mr Asif Jah ...

  22. Mr Bruce Daniels

  23. Dr Cedric Ghevaert

    Cedric Gevaert graduated from the medical school of the University Libre de Bruxelles in 1997 and subsequently became a fellow of the Royal College of Physicians, London (2000). He specialised in Haematology and became a fellow of the Royal College of...

  24. Dr Christine Parkinson

  25. Dr Charalampos Pitsalidis

  26. Dr Joanna Baxter

    The Cambridge Blood and Stem Cell Biobank is a facility of over 6000 viable and nucleic acid samples, the majority from patients with haematological malignancy and clonal blood cell disorders; and the remainder, around 20%, from normal individuals,...

  27. Dr Alex Cagan

    ... are constantly acquiring mutations. Some of these mutations may influence cellular phenotypes, such as growth, resulting in clonal ... of clones. These processes drive cancer progression and may contribute to ageing.  Due to technical limitations until recently these ...

  28. Mrs Cherry May Sanchez

  29. Dr Daniel Hodson

    ... new therapeutic agents that are entering trials for lymphoma may exert some of their effect though changes in translation and conversely how resistance to these agents may arise by feedback mechanisms acting at the level of mRNA translation. ...

  30. Professor Steve Charnock-Jones

    ... basic biological mechanisms underlying angiogenesis which may be perturbed under pathological conditions and are also open to therapeutic ...

  31. Professor Evis Sala

    Now based in Rome, my research in Cambridge focused on integrated diagnostics, through the clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and metabolic tumour habitat imaging...

  32. Professor Fiona Gilbert

    ... in this area examining new oncological radiotracers which may be valuable as biomarkers for patient care or in drug development. ...

  33. Dr Gerry Crossan

    ... of these genes, and the characterization of their products may profoundly contribute to our understanding of pathways that maintain ...

  34. Professor Jason Carroll

    ... properties of Pioneer factors since we believe that these may constitute a mechanism of blocking ER from binding to chromatin; an event that may permit inhibition of ER driven transcription, even in situations where ...

  35. Miss Joanne Mayhew

  36. Dr Kevin Chalut

    ... mechanics, and am studying how these physical properties may play a role in biological processes such as tumorogenesis and ...

  37. Dr Ali Amin Al Olama

    ... has focused on discovery of genetic risk factors of prostate cancer through genome-wide association studies and fine-mapping. I am a core member of an international consortium PRACTICAL (Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the ...

  38. Dr Andreas Bender

    ... large amounts of chemical or biological data related to cancer drug discovery you are very welcome to contact me to see in which way I ...

  39. Dr Alejandra Bruna

    ... aimed to study the effects of the TGF-beta pathway in breast cancer stem cell (BCSC) regulation. To define a role of the TGF-beta pathway in ... of human BCSCs, we have analyzed a panel of breast cancer cell lines that represent the molecular heterogeneity present in primary ...

  40. Professor Antonis Antoniou

    ... component; - the identification and characterisation of cancer risks for genetically susceptible individuals, such as those carrying ...

  41. Dr Alison Dunning

    Work in the Centre for Cancer Genetic Epidemiology "wet lab" involves running very high throughput ... (NGS) studies. We search for genetic risk factors for both cancer susceptibility and treatment-response. In this we collaborate closely ... consortia for breast, ovarian, endometrial and prostate cancer association studies: BCAC http://bcac.ccge.medschl.cam.ac.uk, CIMBA ...

  42. Dr Ashray Gunjur

    ... broadly interested in immuno-oncology and the link between cancer and the gut microbiome, and am undertaking a PhD supervised by Dr David ... between gut microbiota and outcomes in patients with rare cancer types. ...

  43. Dr Ahsan MEMON

    ... this holographic system was deployed to the study of cancer and stem cell shape regulation and the role of effective membrane ...

  44. Dr Aisling Redmond

    ... She completed postdoctoral fellowships in the breast cancer field at the Royal College of Surgeons in Ireland and Cancer Research UK Cambridge Institute (with Professor Jason Carroll), ...

  45. Professor Alan Warren

    ... how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome, containing ... it is also important for oncogenesis: a novel class of human cancer predisposition disorder has recently emerged that is caused by mutations ...

  46. Dr Alexey Larionov

    Hormonal treatment and resistance in Breast cancer Heritable cancer predisposition NGS data ...

  47. Dr Simon Cook

    ... cells adapt to long term exposure to these drugs ('acquired resistance') and the remodelling of signalling pathways that this entails. ...

  48. Dr Pippa Corrie

    ... targeted therapies, to identify molecular response and resistance mechanisms. I work with Duncan Jodrell and Bristi Basu in the ...

  49. Ms Fiona Morgan

    ... cancer patient survival, by finding routes to overcome drug resistance and eventually enabling earlier cancer detection. The cancer models ...

  50. Dr Gaia Schiavon

    ... to interrogate minimal residual disease - Acquired therapy resistance mechanisms in ER positive breast cancers - Novel biomarkers and ...

  51. Dr Geoff Macintyre

    ... of genomic copy-number changes associated with treatment resistance in high-grade serous ovarian cancer (HGSOC). These methods are ...

  52. Mr Harveer Dev

    ... relate to disease progression, treatment response and drug resistance in the clinic. This will allow us to better identify and stratify ...

  53. Dr Hedley Carr

    ... measure biomarkers and further understanding of response and resistance across a range of drug discovery and clinical development programmes ...

  54. Dr Ashwin Seshia

    One of the research thrusts in my group is the development of microelectromechanical and microfluidics based platforms for early diagnosis. We also research microfabricated biophysical tools to characterise biological systems at the molecular, cellular...

  55. Professor Andrew Flewitt

    I work in large area electronics and MEMS devices, with a particular focus on acoustic wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic pumps without...

  56. Dr Annalisa Mupo

    Acute myeloid leukemia (AML) is a molecularly diverse malignancy representing 15-20% of all childhood and around 35% of all adult leukemias. My work aims to study commonly occurring mutations in AML-NK (normal karyotype) using sophisticated mouse models.

  57. Mr Alex Frankell

    Interpretation of Genomic data to inform in vitro molecular analysis and identify important drivers of Oesophageal adenocarcinoma carcinogenesis and Barrett's oesophageal progression. My project focuses on genomic aberrations in the Transforming growth...

  58. Dr Andrew Bannister

    I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes ...

  59. Dr Anna Piskorz

    I’m a molecular biologist focus on translational research in high grade serous ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better...

  60. Dr Tony Jackson

    Proteomic approaches to plasma-membrane assemblies: Membrane proteins cluster together selectively as spatially-restricted, functionally integrated complexes. This can play an important role in many biological processes, including signal transduction....

  61. Dr Alvis Brazma

    High throughput (microarray, sequencing) data analysis. Data integration. Cell cycle. I am in charge of running and developing the transcriptomics data repository ArrayExpress.

  62. Professor Adrian Liston

    We are focussed on understanding the biology of regulatory T cells within the tissues. How they migrate there, what controls their numbers and their functions, both immunological and tissue homeostatic in nature. Our approach is to identify key unknowns...

  63. Dr Adrien Hallou

    Initially trained as a physicist and a chemist at the Ecole Normale Supérieure (Paris, France), I developed my interest for quantitative approaches of biological systems during my MPhil and PhD in Biophysics at the University of Cambridge. I am now a...

  64. Dr Arnaud Comment

    Development of hyperpolarization techniques based on dynamic nuclear polarization (DNP) for magnetic resonance spectroscopy and imaging in particular for biomedical applications. My research is focused on three main axes: Methodology in DNP, including...

  65. Dr Julian Sale

    ... understanding its control is central to understanding cell transformation. We study these processes using the powerful combination of ...

  66. Dr Marc de la Roche

    ... form of the Wnt signaling pathway drives the malignant transformation of intestinal epithelial stem cells leading to tumorigenesis. My ...

  67. Dr Marco Sciacovelli

    ... focuses on the role of metabolic reprogramming during transformation and tumour evolution. We are interested in kidney cancer and we ...

  68. Dr Rafael Romero Garcia

    ... margin to minimise the potential for recurrence or malignant transformation. Maximising the resection whilst minimising harm is complicated ...

  69. Mr Robert Kupp

    Project: Mechanism of neural stem cell transformation by C11orf95-RELA translocation. ...

Pages