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  1. Dr Catherine Lindon

    ... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...

  2. Dr Athena Matakidou

    ... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...

  3. Dr Mariann Bienz

    ... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...

  4. Dr Dario Bressan

    ... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...

  5. Dr Frank McCaughan

    My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...

  6. Professor Gillian Murphy

    ... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...

  7. Dr James Nathan

    Cellular mechanisms of oxygen and metabolite sensing: ...

  8. Dr James Rudd

    ... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...

  9. Ms Paola Marco

    ... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...

  10. Dr Marisa Segal

    ... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...

  11. Dr David Gilligan

    David Gilligan is a Consultant Clinical Oncologist at Addenbrooke's and Papworth Hospitals in Cambridge. He is the Clinical Lead for Acute Oncology at Addenbrooke's. He trained in pre clinical medicine at the University of Edinburgh and clinical...

  12. Mr David Thurtle

    Radiological assessment of prostatic osseous metastases. Robotic-assisted laparoscopic prostatectomy. Early detection of prostate cancer. Risk Prediction in prostate cancer

  13. Professor David Glover

    Our laboratory studies the regulation of progression through mitosis and meiosis in animal cells. The high degree of evolutionary conservation of these regulatory mechanisms means that findings in model organisms are readily applicable to human cells....

  14. Dr Roisin Owens

    Our group works on integrating biological models with electronic devices to generate systems that can be predictive of real biological systems, for drug discovery and therapeutics. We combine expertise in a wide range of disciplines including...

  15. Mr Thierry Lefebvre

    Radiotherapy is often prescribed in oncology clinics to treat solid tumours and to limit the development and the propagation of cancer cells. The lack of oxygenation seen in some tumour regions under chaotic and unrestricted cellular growth constitute a...

  16. Professor Walid Khaled

    My laboratory works on defining the early cellular and molecular events that drive tumour initiation and development. In particular, we focus on how the cell of origin affects the differentiation trajectory of nascent tumour cells and dictates changes...

  17. Miss Alexandra Hart

  18. Miss Annie Howitt

  19. Mr Andrew Lee

  20. Mr Alex Frankell

    Interpretation of Genomic data to inform in vitro molecular analysis and identify important drivers of Oesophageal adenocarcinoma carcinogenesis and Barrett's oesophageal progression. My project focuses on genomic aberrations in the Transforming growth...

  21. Dr Alex Samoshkin

    I have been a Translational Technology Manager in the University of Cambridge since 2017. My primary role is to connect researchers in technology/physical sciences with clinicians and academics to develop new collaborative translational projects. I...

  22. Dr Andrew Trinh

  23. Dr Chiwen Chang

    1. Interaction between NK cells and HLA Class I antigen during immune response. 2. Immunotherapy for cancers and autoimmune diseases.

  24. Dr Emeka Chuks Okonji

  25. Dr Christopher Foley

  26. Mr David Palmer

  27. Dr Alex Cagan

    ... are constantly acquiring mutations. Some of these mutations may influence cellular phenotypes, such as growth, resulting in clonal ... of clones. These processes drive cancer progression and may contribute to ageing.  Due to technical limitations until recently these ...

  28. Mrs Cherry May Sanchez

  29. Dr Daniel Hodson

    ... new therapeutic agents that are entering trials for lymphoma may exert some of their effect though changes in translation and conversely how resistance to these agents may arise by feedback mechanisms acting at the level of mRNA translation. ...

  30. Professor Steve Charnock-Jones

    ... basic biological mechanisms underlying angiogenesis which may be perturbed under pathological conditions and are also open to therapeutic ...

  31. Professor Evis Sala

    Now based in Rome, my research in Cambridge focused on integrated diagnostics, through the clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and metabolic tumour habitat imaging...

  32. Professor Fiona Gilbert

    ... in this area examining new oncological radiotracers which may be valuable as biomarkers for patient care or in drug development. ...

  33. Dr Gerry Crossan

    ... of these genes, and the characterization of their products may profoundly contribute to our understanding of pathways that maintain ...

  34. Professor Jason Carroll

    ... properties of Pioneer factors since we believe that these may constitute a mechanism of blocking ER from binding to chromatin; an event that may permit inhibition of ER driven transcription, even in situations where ...

  35. Miss Joanne Mayhew

  36. Dr Kevin Chalut

    ... mechanics, and am studying how these physical properties may play a role in biological processes such as tumorogenesis and ...

  37. Professor Heike Laman

    F-box proteins (FBPs) are the substrate-recruiting subunits of SCF (Skp1-cullin1-FBP)-type E3 ubiquitin ligases, but ubiquitinated substrates have been identified for only a few of the sixty-nine FBPs identified in humans. The major aim of my laboratory...

  38. Dr Maria Christophorou

    How do the cells of an organism, all of which have exactly the same genetic code, adopt such different fates, morphologies and functions? And how do they then respond to the signals and stresses around them in order to make up a living, growing,...

  39. Dr Namshik Han

    I am a computational drug discovery scientist, coming from a background in machine learning, computational biology, cancer genomics and cancer epigenomics. I am Head of Computational Research & AI at Milner Therapeutics Institute in University of...

  40. Dr Andrew Gee

    Since 1995, I have been working on technical aspects of clinical ultrasonic imaging, with particular emphasis on three-dimensional imaging and elastography (stiffness imaging). Along with Richard Prager and Graham Treece, I lead the Medical Imaging...

  41. Dr Andre Neves

    ... cancer diagnosis and for better assessing response to cancer therapy. Currently, I'm planning a first-in-human clinical trial of a novel ...

  42. Dr Richard Benson

    Interests based around improving radiotherapy and chemoradiotherapy in head and neck and urological cancers, develpoing technical radiotherapy and evaluating treatment related toxicity.

  43. Professor Bertie Gottgens

    ... blood stem/progenitor cell populations used in cell and gene therapy protocols. ...

  44. Professor Kevin Brindle

    ... techniques to detect the early responses of tumours to therapy, with a view to translating these into clinical application. This has ...

  45. Dr Camilo Colaco

    Developing cancer therapy as opposed to research. Autologous tumour-dendritic cell fusion hybrids ...

  46. Dr Camilo Colaco

  47. Dr Christopher Jones

    My research focuses on improving the radiation response and post-radiation monitoring of oesophageal cancers, with a particular focus on oesophageal adenocarcinoma. I am also interested in the study of radiotherapy-related genomic evolution.

  48. Dr Claire Connell

    Pancreatic cancer and immunotherapy

  49. Dr Amos Burke

    ... Institute Lymphoma Clinical Studies Group and chairs its paediatric Non-Hodgkin Lymphoma subgroup. He has local laboratory ...

  50. Dr Anny Wong

    ... training new staff and overseeing the smooth running of the paediatric day unit where children come for their treatment and investigations. ...

  51. Professor David Rowitch

    ... critical roles played by downstream transcription factors in paediatric medulloblastoma and glioma. ...

  52. Mrs Gill Kortum

    Programme Manager for both the Paediatric Cancer and Neuro-oncology programmes in the CRUK Cambridge Centre. ...

  53. Dr Mae Goldgraben

    ... contribution of the miRNA processing pathway in certain paediatric cancers, using NGS technologies and bioinformatics. I am also ...

  54. Dr Liz Hook

    ... pathology learning. I provide clinical sessions in paediatric histopathology at CUHNHSFT. My particular fields of interest are solid and haematological paediatric neoplasms. I am joint training lead for the Histopathology ...

  55. Professor Marc Tischkowitz

    Marc Tischkowitz is a Professor and Honorary NHS Consultant in the Department of Medical Genetics at Cambridge. He completed his medical degree in 1993 and trained in Medical Oncology before completing his CCST in Medical Genetics. From 1999-2002 he...

  56. Dr Michael Gattens

    I have been a consultant in paediatric haematology in Addenbrooke's since 2004. I am responsible for the ... for trials of new haemophilia factor concentrates in paediatric haemophilia patients. I have one non-malignant haematology ... also seen in our haemophilia centre, which has specialist paediatric clinics once per month. I have a particular interest in safeguarding ...

  57. Professor Matthew Allen

    ... of musculoskeletal cancer, with a particular emphasis on paediatric cancers (such as osteosarcoma, rhabdomyosarcoma and Ewings sarcoma) ...

  58. Mr Oscar Baldwin

    ... focuses on choroid plexus carcinoma (CPC), an extremely rare paediatric brain cancer. Currently, there is a lack of understanding as to how ...

  59. Dr Andrew Gill

    ... apply computational methods to the analysis of MR images of tumours. I have in the past specialised in pharmacokinetic modelling of DCE-MRI ...

  60. Mr Angelos Kolias

    ... His clinical interests include surgery for brain tumours (special interest in skull base/pituitary surgery), neuroendoscopy, ...

  61. Dr Simon Cook

    ... receptors, KRAS, BRAF or PI3K (or PTEN loss). As a result, tumours frequently evolve to be 'addicted' to these oncoproteins or the ... pathway. We are interested in understanding why some tumours are intrinsically resistant to such drugs, how cells adapt to long term ...

  62. Professor Daniel St Johnston

    Most tumours arise from epithelial tissues composed of polarised cells that stick ... to form sheets, and a loss of polarity is a hallmark of tumours. We investigate how polarity is established in different epithelial ...

  63. Dr David Fernandez-Antoran

    ... is to understand the effects of ionising radiation in tumours and normal tissues and set the basis for designing external ...

  64. Dr David Sargan

    ... We are also applying cytogenetic analyses to the same tumours. ...

  65. Dr Emmanuel Huguet

    ... and his specialty interests are surgical treatments of tumours of the liver, biliary tree and pancreas. ...

  66. Professor Ferdia Gallagher

    ... of cancer as well as methods to assess early response of tumours to treatment with chemotherapy. ...

  67. Dr Fiona Harris

    Consultant Clinical Oncologist, Consultant in CNS tumours, TYA lead, CNS tumours in both the adult and teenage and young adult population ...

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