Search results
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Dr Catherine Lindon
... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...
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Dr Athena Matakidou
... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...
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Dr Mariann Bienz
... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...
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Dr Dario Bressan
... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...
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Dr Frank McCaughan
My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...
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Professor Gillian Murphy
... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...
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Dr James Nathan
Cellular mechanisms of oxygen and metabolite sensing: ...
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Dr James Rudd
... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...
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Ms Paola Marco
... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...
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Dr Marisa Segal
... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...
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Professor Simon Mendez-Ferrer
The Méndez-Ferrer laboratory research focuses on the regulation of the haematopoietic stem-cell niche in health and disease. Blood stem cells reside in specialised niches which allows them to self-renew, proliferate, differentiate and migrate according...
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Miss Ariella Stewart
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Dr Annalisa Mupo
Acute myeloid leukemia (AML) is a molecularly diverse malignancy representing 15-20% of all childhood and around 35% of all adult leukemias. My work aims to study commonly occurring mutations in AML-NK (normal karyotype) using sophisticated mouse models.
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Dr Anne Warren
Responsible for providing histopathological support and tissue sampling and assessment for research projects of the urological malignancies research programme.
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Dr Cinzia Esposito
Hypoxia signalling
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Dr Christine Farr
I am interested in chromosome biology and the relationship between the structural organisation of vertebrate chromosomes and their function. Previously we have derived a minimal human chromosome, studied de novo telomere formation and genetically...
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Mr Calvin Cheah
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Ms Danya Cheeseman
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Dr Dominick McIntyre
Head of the CRUK CI Imaging Core Facility, specialising in preclinical MRI and image databases, and running a team supporting research in clinical & preclinical MR, BLI/FLI, CT and radionuclide imaging, and ultrasound.
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Dr Shiqing Mao
DNA modifications
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Dr Elisa Laurenti
Daily blood cell production is guaranteed throughout life by a hierarchy with haematopoietic stem cells (HSC) at its root. HSC are very different from other haematopoietic cell types and have unique functional properties, such as their infrequent...
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Dr Adrien Hallou
Initially trained as a physicist and a chemist at the Ecole Normale Supérieure (Paris, France), I developed my interest for quantitative approaches of biological systems during my MPhil and PhD in Biophysics at the University of Cambridge. I am now a...
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Professor Andrew Flewitt
I work in large area electronics and MEMS devices, with a particular focus on acoustic wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic pumps without...
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Dr Andrew Bannister
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes ...
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Dr Simon Cook
In terms of basic science we are interested in how protein kinase and lipid signalling pathways control cell fate decisions such as proliferation versus differentiation and survival versus death. However, these pathways are frequently de-regulated in...
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Dr David Adams
David performs forward genetic screens to uncover cancer genes and pathways and leads a programme to decode the genomes of several mouse strains. He also leads the Mouse Genomes Project and the Mouse Genetics Project. The Mouse Genomes Project is...
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Professor Eric Miska
Our main goal is to understand how cells interpret genetic and epigenetic information as well as environmental cues to determine their correct cell fate, i.e. to make the decision to divide, die or differentiate. The recent discovery of a large...
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Professor Evis Sala
Now based in Rome, my research in Cambridge focused on integrated diagnostics, through the clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and metabolic tumour habitat imaging...
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Dr Helen Morris
In the Primary Care Unit I've managed and collaborated on a number of randomised controlled trials and other well-designed studies in the field of cancer and genetics in a primary care setting: 1) The GRAIDS (Genetic Risk Assessment on the Internet and...
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Professor Heike Laman
F-box proteins (FBPs) are the substrate-recruiting subunits of SCF (Skp1-cullin1-FBP)-type E3 ubiquitin ligases, but ubiquitinated substrates have been identified for only a few of the sixty-nine FBPs identified in humans. The major aim of my laboratory...
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Dr David Fairen-Jimenez
Our research concerns the study of the molecular mechanisms that control adsorption processes in porous materials. We are particularly interested in drug delivery systems, where nanotechnology has a fundamental impact to revolutionise cancer diagnosis...
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Miss Jamie McGinn
Project title: Epithelial cell dynamics during postnatal growth; relevance for ...
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Dr Ali Amin Al Olama
... at highest risk of developing prostate cancer could be useful for prevention and screening programs. ...
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Mr Arqum Anwar
... the cellular role(s) of a novel factor expected to be involved in DNA damage response. Specifically, the interactome of the protein will be explored using co-immunoprecipitation followed by mass spectrometry. The ...
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Dr Andreas Bender
Previously affiliated with the Lead Discovery Informatics (LDI) group of Novartis in Cambridge/MA, I am now developing and applying cheminformatics techniques in the drug discovery field in my group with the University of Cambridge. Our expertise ranges...
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Dr Alejandra Bruna
... An integrated bioinformatic analysis found this signature to be a prognostic pathway signature in ER-/basal human breast cancer. We are now ...
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Professor Adrian Liston
We are focussed on understanding the biology of regulatory T cells within the tissues. How they migrate there, what controls their numbers and their functions, both immunological and tissue homeostatic in nature. Our approach is to identify key unknowns...
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Dr Alison Dunning
Work in the Centre for Cancer Genetic Epidemiology "wet lab" involves running very high throughput SNP-chip genotyping and Next Generation Sequencing (NGS) studies. We search for genetic risk factors for both cancer susceptibility and treatment-response...
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Dr Ashray Gunjur
I am an early-career medical oncologist from Melbourne, Australia. I am broadly interested in immuno-oncology and the link between cancer and the gut microbiome, and am undertaking a PhD supervised by Dr David Adams and Dr Trevor Lawley (Wellcome...
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Dr Ahsan MEMON
Ahsan has developed a sui generis versatile holographic system capable of diverse photo-perturbation techniques including photo-manipulation, photo-activation, photo-ablation, optical-trapping and optogenetics, combined with multi-modal imaging...
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Professor Sir Bruce Ponder
... enriched for genes associated with the 72 GWAS loci formally confirmed at the time of our analysis. These regulons and their TFs show ...
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Professor Daniel St Johnston
Most tumours arise from epithelial tissues composed of polarised cells that stick together to form sheets, and a loss of polarity is a hallmark of tumours. We investigate how polarity is established in different epithelial tissues in flies and mammals,...
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Dr Emmanuel Huguet
... laboratories of the Institute of Molecular Medicine at the John Radcliffe Hospital. He carried out initial surgical training in Oxford, ...
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Dr Ewan St John Smith
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Professor John Griffiths
I am retired, and my lab is closed. I am working on completing papers on all the projects that my group performed but failed to publish.
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Professor John Doorbar
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Mr John Latimer
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Dr John Suckling
Our research programme leverages two decades of advancements in magnetic resonance imaging and assocaited methodologies to accrue the evidence to inform the difficult discussions with patients with brain tumours, and their families, on the balance...
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Mr John Benson
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Dr John Bradley
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Dr John Grant
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Mr Kourosh Saeb-Parsy
... immunotherapies. In collaboration with colleagues at the Gurdon Institute, AstraZeneca and Medimmune, I lead a programme to investigate ...
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Professor Tony Kouzarides
... at the University of Cambridge, Deputy Director of the Gurdon Institute and Director of the Milner Therapeutics Institute. Tony ... He returned to Cambridge to lead a research group at the Gurdon Institute. Tony's research group at the Gurdon Institute is focused ...
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Professor Anna Philpott
I am interested in the balance between proliferation and differentiation during development and cancer, using a range of models including embryos of the frog Xenopus laevis, mammalian cells including ES cells, and mice. I am particularly interested in...
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Dr Birgitta Olofsson
From VEGF-B, vasculogenesis in zebrafish and hemocyte function in drosophila to optimal foraging in C.elegans. Never a dull moment!
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Mrs Catherine Towns
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Professor David Glover
Our laboratory studies the regulation of progression through mitosis and meiosis in animal cells. The high degree of evolutionary conservation of these regulatory mechanisms means that findings in model organisms are readily applicable to human cells....
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Dr Ian McGough
Alterations in intercellular signalling pathways are often the initiating event in carcinogenesis. A prime example being hyperactivation of the Wnt signalling pathway in colon cancer due to loss of function mutations in APC. Cell-to-cell signalling...
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Dr Michael Gattens
I have been a consultant in paediatric haematology in Addenbrooke's since 2004. I am responsible for the care of children with malignant and non-malignant haematological conditions, accepting referrals from the East of England region. I am principal...
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Dr Philip Zegerman
The Regulation of Replication Initiation in Eukaryotes Faithful inheritance of the genome from mother to daughter cell requires that it is replicated accurately, in its entirety, exactly once. Failure to perfectly replicate the genome is a likely source...
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Dr Phil Jones
Our group studies how normal cell behaviour is altered by mutation in the early stages of cancer evolution. We focus on squamous tissues, the skin epidermis and the lining of the oesophagus, using transgenic models, novel sequencing approaches in human...
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Dr Philip Earwaker