Search results
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Dr Catherine Lindon
... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...
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Dr Athena Matakidou
... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...
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Dr Mariann Bienz
... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...
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Dr Dario Bressan
... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...
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Dr Frank McCaughan
My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...
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Professor Gillian Murphy
... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...
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Dr James Nathan
Cellular mechanisms of oxygen and metabolite sensing: ...
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Dr James Rudd
... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...
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Ms Paola Marco
... The inhibitor can be washed out, allowing us to study events in a more flexible way. I will introduce these mutants in RPE cells to ...
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Dr Marisa Segal
... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...
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Professor Simon Mendez-Ferrer
The Méndez-Ferrer laboratory research focuses on the regulation of the haematopoietic stem-cell niche in health and disease. Blood stem cells reside in specialised niches which allows them to self-renew, proliferate, differentiate and migrate according...
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Miss Ariella Stewart
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Miss Anita Balakrishnan
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Dr Alejandra Bruna
We aimed to study the effects of the TGF-beta pathway in breast cancer stem cell (BCSC) regulation. To define a role of the TGF-beta pathway in the regulation of human BCSCs, we have analyzed a panel of breast cancer cell lines that represent the...
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Professor Antonis Antoniou
My main research interest is the development and application of statistical modelling techniques for addressing clinical questions, and the development of risk prediction tools which are used in clinical practice. ...
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Dr Aideen Daly
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Miss Alicia Gonzalez Diaz
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Mr Arman Ghodsinia
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Professor Andrew Flewitt
I work in large area electronics and MEMS devices, with a particular focus on acoustic wave devices using thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic pumps without...
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Professor Alan Warren
Our long-term goal is to elucidate the molecular mechanisms of ribosome assembly in eukaryotic cells and to understand how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome,...
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Dr Alan Barnicle
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Professor Duncan Jodrell
I endeavour to integrate and optimise the pre-clinical development and science-led clinical application of novel therapies and novel therapeutic combinations, including first into man (phase I) and associated studies. My research goal is to identify...
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Dr Kathryn Chapman
Kathryn Chapman is the Deputy Director of the Milner Therapeutics Institute, a dynamic partnership between pharmaceutical companies and academics at the University of Cambridge and associated Institutes. Its mission is to connect the intellectual know...
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Professor Vincent Gnanapragasam
Vincent J Gnanapragasam holds a personal Chair in Urology at the University of Cambridge and is an Honorary Consultant Urologist at Addenbrooke’s Hospital, Cambridge. He graduated from Newcastle University and following basic surgical training, was...
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Dr Roy Rabbie
We use DNA sequencing of patients and their tumours to study genomic evolution in melanoma.
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Dr Ashwin Seshia
... biophysical tools to characterise biological systems at the molecular, cellular and multi-cellular scales. ...
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Dr Ahsan MEMON
... measure local forces, and re-localise or switch cellular and molecular behaviour. As one of its first applications, this holographic ...
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Dr Annalisa Mupo
Acute myeloid leukemia (AML) is a molecularly diverse malignancy representing 15-20% of all childhood and around 35% of all adult leukemias. My work aims to study commonly occurring mutations in AML-NK (normal karyotype) using sophisticated mouse models.
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Mr Alex Frankell
Interpretation of Genomic data to inform in vitro molecular analysis and identify important drivers of Oesophageal adenocarcinoma ...
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Dr Anna Piskorz
I’m a molecular biologist focus on translational research in high grade serous ... (blood, plasma, ascites). I have a special interest in molecular characterisation of ascites samples from HGSOC patients. My research ... close collaboration with Addenbrook’s hospital and Cancer Molecular Diagnostic Laboratory. I’m engaged in several clinical trails ...
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Dr Tony Jackson
Proteomic approaches to plasma-membrane assemblies: Membrane proteins cluster together selectively as spatially-restricted, functionally integrated complexes. This can play an important role in many biological processes, including signal transduction....
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Professor Tony Green
... myeloproliferative neoplasms. The Green lab is studying the molecular and cellular mechanisms whereby aberrant JAK/STAT signalling subverts ...
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Dr Arnaud Comment
... in the numerous metabolic reactions taking place in vivo. Molecular Imaging by MR imaging, a recent discipline combining molecular biology and in vivo imaging, aims at differentiating tissues based ...
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Professor Eamonn Maher
Eamonn Maher is Professor of Medical Genetics and Genomic Medicine and Head of the Department of Medical Genetics. Prior to taking up this post in 2013 he was Professor of Medical Genetics and Academic Lead for the Centre for Rare Diseases and...
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Mr Arqum Anwar
Rotation Project: The project aims to investigate the cellular role(s) of a novel factor expected to be involved in DNA damage ...
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Dr Adrien Hallou
... with wet lab biology experiments to understand the role of cellular heterogeneity in cell fate decision, pattern formation and tissue ...
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Dr Alex Cagan
... acquiring mutations. Some of these mutations may influence cellular phenotypes, such as growth, resulting in clonal expansions. Over time ...
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Professor Brian Huntly
Our aim is to further characterise the molecular and cellular biology of cancer stem cells and to compare and contrast these to ...
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Dr Bristi Basu
I co-lead the Cambridge Experimental Cancer Medicine Centre with Prof Duncan Jodrell and the CRUK Cambridge Centre Pancreatic Cancer Programme with Dr Giulia Biffi. Other roles include Capacity Building leadership team within the Cambridge NIHR...
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Dr Claudia Ribeiro de Almeida
... against pathogens, while maintaining genome stability and cellular homeostasis. ...
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Professor Adrian Liston
... they migrate there, what controls their numbers and their functions, both immunological and tissue homeostatic in nature. Our approach is ...
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Dr Francesco Colucci
... methods, mass cytometry (CyTOF) to analyse phenotype and functions of single NK cells in heterogeneous cell populations. Work in our lab ...
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Professor Heike Laman
... The challenge we face is to understand the network of functions that has been compromised by the loss of the FBP that is causing ...
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Professor Julie Ahringer
We investigate the functions chromatin regulatory complexes implicated in human disease using the ...
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Professor John Trowsdale
Immunogenetics and functions of the MHC Immunogenetics of NK receptors and related molecules ...
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Dr Lori Passmore
... and its length can be regulated to influence these functions. For example, shortening of the poly(A) tail can decrease the ...
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Dr Marc de la Roche
... and chemical loss-of-function. I am also interested in the functions of tankyrase, a protein that covalently modifies proteins with ... by a battery of 17 PARylase enzymes with diverse biological functions. Tankyrase itself regulates Wnt signaling, the insulin-responsive ...
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Dr Maria Christophorou
... genetic code, adopt such different fates, morphologies and functions? And how do they then respond to the signals and stresses around them ... proteins, which then go on to execute most of the cell’s functions, are themselves subject to regulatory mechanisms that determine when, ...
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Dr Sumru Bayin
... for skilled motor movements and higher order cognitive functions. Its protracted development makes the neonatal cerebellum susceptible ...
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Professor Andrea Brand
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Dr Alvis Brazma
... (microarray, sequencing) data analysis. Data integration. Cell cycle. I am in charge of running and developing the transcriptomics data ...
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Dr Adeeba Fathima Valiya Thodiyil
Single cell/Tissue imaging, quantitative microscopy, image analysis ...
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Dr Adrian Ionescu
... Training Network project, SIMDALEE2, studying low energy electron interactions with matter. In this position I have had the opportunity ...
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Dr Charalampos Pitsalidis
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Professor George Malliaras
Prof. Malliaras’ group is interested in bioelectronics. Research themes include the design and validation of implantable and cutaneous devices to interface with the brain, with the aim of understanding and treating neurological disorders.
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Dr Guozhen Wang
We work on the aggregation mechanism of the tumor suppressor protein, p53, and developing novel anti-cancer drugs that function by inhibiting aggregation of mutant p53.
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Dr Hannah Harrison
Since moving into public health research around 5 years, Hannah has been involved in projects investigating risk-stratification for kidney cancer screening and follow-up. Her most rencet project, funded by CRUK, is investigating multifactorial models...
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Professor Ruth Cameron
My research concerns medical materials. We design, produce and characterise materials designed for use within the body, materials for pharmaceutics and materials to provide controlled three dimensional environments for cells.
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Dr Roisin Owens
Our group works on integrating biological models with electronic devices to generate systems that can be predictive of real biological systems, for drug discovery and therapeutics. We combine expertise in a wide range of disciplines including...
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Dr Steven Bell
I am an Epidemiologist based within the Precision Breast Cancer Institute , Department of Oncology at the University of Cambridge. At present my work utilises next-generation sequencing data alongside bioinformatic approaches to obtain insights...
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Professor Anthony Davenport
... pharmacology and in vivo imaging using positron emission tomography, to determine how these are altered with disease. Major interests ...
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Dr Iosif Mendichovszky
... and prostate cancers using single photon emission computed tomography (SPECT), positron emission tomography (PET) and magnetic resonance imaging (MRI). I am also involved in ...
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Dr Franklin Aigbirhio
... for the in vivo imaging technique of positron emission tomography. Objectives are to design, develop and apply imaging probes that are ...