Search results
-
Mr Angelos Kolias
... and international collaborators, he has published impactful papers in journals such as the NEJM, Lancet, PLOS Medicine, Annals of Surgery, ...
-
Professor Eamonn Maher
... of Birmingham. Eamonn has published around 400 research papers in scientific journals as well as reviews and book chapters in the ...
-
Professor John Griffiths
... retired, and my lab is closed. I am working on completing papers on all the projects that my group performed but failed to publish. ...
-
Dr Kelly Holmes
... factors in breast cancer. During this time she published key papers which catalysed exploring key transcription factors as drug targets. ...
-
Mr Nick Screaton
... has published widely on cardiothoracic imaging with over 50 papers, has served as research and education lead for the British Society of ...
-
Professor Vincent Gnanapragasam
... This collaborative has so far produced >70 peer reviewed papers with a combined grant income of >£6M. Most recently this group ... £6M as co-investigator and published over 200 peer reviewed papers. He is also joint applicant on research collaboratives that have secured ...
-
Miss Patrisha Altea
-
Dr Amos Burke
Dr Amos Burke is a childhood cancer specialist working at Addenbrooke's providing a service for chidlren in the East of England. He has a particular interest in childhood lymphomas and is a member of the National Cancer Research Institute Lymphoma...
-
Dr Anny Wong
Dr Anny Wong is a childhood cancer specialist working at Addenbrooke's. Her role includes training new staff and overseeing the smooth running of the paediatric day unit where children come for their treatment and investigations. She also specialises...
-
Dr Andre Neves
As a chemical engineer, I enjoy translating basic science into novel biomedical technologies. I am interested in the use of molecular imaging techniques for early cancer diagnosis and for better assessing response to cancer therapy. Currently, I'm...
-
Professor David Rowitch
New insight into human neurological diseases has emerged from investigation of normal pathways of brain development. Dr. Rowitch's laboratory investigates Sonic hedgehog (Shh) and BRAF signaling in regulation of neural stem cells that can give rise to...
-
Dr Dorentina Bexheti
Development and validation of quantitative LC-MS/MS methods for the analysis small molecules and metabolites/biomarkers in biological matrices, cancer tissues and cells, using different sample preparation techniques.
-
Mrs Gill Kortum
Programme Manager for both the Paediatric Cancer and Neuro-oncology programmes in the CRUK Cambridge Centre.
-
Professor Gillian Murphy
The Murphy Group studied cell surface proteinases that modulate both the extracellular matrix and the activities of key cytokines and growth factors and have generated information on their structure function relationships that are key to the...
-
Dr Mae Goldgraben
My research is focused on the genetically inherited contribution of the miRNA processing pathway in certain paediatric cancers, using NGS technologies and bioinformatics. I am also developing PCR & NGS-based assays for extracted blood DNA to identify...
-
Dr Ian McGough
Alterations in intercellular signalling pathways are often the initiating event in carcinogenesis. A prime example being hyperactivation of the Wnt signalling pathway in colon cancer due to loss of function mutations in APC. Cell-to-cell signalling...
-
Dr Andrew Bannister
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes ...
-
Dr Claire Crafter
... targetting the PI3 Kinase pathway, particularly the AKT inhibitor AZD5363 and the mTORC1/2 inhibitor, AZD2014. I also have a stong interest in combination screening and ...
-
Dr Simon Cook
... or are entering the clinic; for example, the MEK1/2 inhibitor AZD6244 which blocks the BRAF-MEK1/2-ERK1/2 signalling pathway. We ...
-
Professor Tim Eisen
I am a clinical trialist interested in developing new treatments for advanced disease, identifying and managing those at risk of disease. My current clinical interests are the research and management of kidney cancer. In kidney cancer I have been...
-
Dr Finian Leeper
My interest lies in applying Organic Synthesis to Biological Problems. Current projects include (a) biosynthesis of prodigiosin - prodigiosin has potent antitumour and immunosuppressive properties and a close relative obatoclax is in clinical trials for...
-
Dr James Tysome
Angiogenesis plays a role in the growth of many skull base and head and neck tumours. I aim to investigate the role of angiogenesis inhibitors in these tumours, develop novel inhibitors including oncolytic viruses and use molecular imaging techniques to...
-
Miss Joanna Brookfield
Drug discovery at CRT working in medicinal chemistry to deliver small molecule inhibitors of cancer targets.
-
Professor Klaus Okkenhaug
... inhibitors in therapeutic settings. Indeed, the PI3Kdelta inhibitor idelalisib is already approved for the treatment of certain B cell ...
-
Dr Phil Jewsbury
... TAGRISSO, and the DNA Damage Response pipeline AZD1775, AZD6738 & AZD0156. Specialties: Oncology drug discovery and development; ...
-
Dr Alejandra Bruna
... the molecular heterogeneity present in primary tumors. In vitro and in vivo assays showed that TGF-beta differentially regulates BCSCs ...
-
Mr Alex Frankell
Interpretation of Genomic data to inform in vitro molecular analysis and identify important drivers of Oesophageal ...
-
Professor Anthony Davenport
... drugs) together with their transmitters in humans. We use in vitro pharmacology and in vivo imaging using positron emission tomography, to ...
-
Dr Arnaud Comment
... biomolecules, and the conception and test of in vivo and in vitro protocols for biomedical applications. Real-time uptake and metabolism, ...
-
Professor Steve Charnock-Jones
... ablation. We also carry out work using human tissues in vitro, in vivo and in retrospective genetics studies. I have other work focused ...
-
Professor Ernest Laue
... of biochemical methods to study cellular complexes both in vitro and in vivo. Studying proteins which control signal transduction ...
-
Dr Emma Rawlins
... to contribute to cancer growth. Our lab also uses in vitro and in vivo techniques to investigate the molecular control of lung ...
-
Miss Samantha Hallawell
Cancer Immunotherapy- In vitro profiling of immunostimulatory antibodies as well as elucidation of ...
-
Dr Hanna Najgebauer
... new algorithms and computational tools for scoring cancer in vitro models based on their clinical relevance and covered genomic ...
-
Professor Alan Warren
... of the large ribosomal subunit. My lab combines in vivo genetic approaches in a variety of model organisms with biochemistry and ...
-
Professor Anna Philpott
I am interested in the balance between proliferation and differentiation during development and cancer, using a range of models including embryos of the frog Xenopus laevis, mammalian cells including ES cells, and mice. I am particularly interested in...
-
Dr Athena Matakidou
... of reproducible and accurate RCC mouse models will allow in-vivo investigations of the underlying tumour biology and the discovery of new ...
-
Professor Kevin Brindle
... for the non-invasive detection of tumour cell death in vivo. ...
-
Dr Catherine Green
... interactions between replication proteins, and also in vivo studies of replication protein dynamics and interactions in human tissue ...
-
Dr Dario Bressan
... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and self-ligating ...
-
Professor David Neal
... on human tissue (ChIP-seq and sequencing) and using in vivo models. These studies are now being extended to man using experimental ...
-
Dr Adelyne Chan
Biology of Ras-induced senescence
-
Dr Claudia Ribeiro de Almeida
B-lymphocytes are cells of the immune system responsible for the production of antibodies, and do so by employing hazardous mechanisms of somatic DNA mutation and DNA deletion-recombination with remarkable efficiency. Increasing evidence suggests a...
-
Dr John Suckling
Our research programme leverages two decades of advancements in magnetic resonance imaging and assocaited methodologies to accrue the evidence to inform the difficult discussions with patients with brain tumours, and their families, on the balance...
-
Dr Matthew Hoare
Cellular senescence and oncogene induced senescence in particular is a potent tumour suppressor mechanism. Hepatocytes from subjects with chronic liver disease demonstrate evidence of senescence which may underpin declining liver function and place...
-
Dr Michael Boemo
My group develops new computational methods to study how dysregulation and errors in DNA replication and mitosis lead to genome instability. We use and develop cutting-edge methodologies from machine learning, bioinformatics, software engineering, high...
-
Dr Ragnhildur Thora Karadottir
... lab’s interest is to understand how signals from neurons induce OPCs to differentiate and myelinate axons during development and with ...
-
Dr Saif Ahmad
I am a senior clinical oncology trainee currently undertaking a Clinical PhD Fellowship at the MRC Cancer Unit in Prof Ashok Venkitaraman's lab. My research is focused on understanding a novel mechanism by which the BRCA2 tumour suppressor protein...
-
Mr Asif Jah
... centres in the UK. Besides performing major liver and pancreatic cancer surgery and liver transplants, he has made significant ... heavily to the development of advanced laparoscopic pancreatic and liver resections, highly specialised regional service for ...
-
Dr Bristi Basu
... with Prof Duncan Jodrell and the CRUK Cambridge Centre Pancreatic Cancer Programme with Dr Giulia Biffi. Other roles include Capacity ... Biomedical Research Centre; NCRI Upper GI Hepatobiliary and Pancreatic Cancer subgroups; Cancer Research UK Clinical Research Committee ...
-
Dr Claire Connell
Pancreatic cancer and immunotherapy
-
Dr Pippa Corrie
... I work with Duncan Jodrell and Bristi Basu in the pancreatic experimental therapeutics programme. ...
-
Mrs Eva Serrao
Despite medical advances, pancreatic cancer still has a 5-year survival rate of less than 6%. The ideal ... detect, grade and follow progression of precursor lesions of pancreatic cancer before any morphological lesion or tumour can be detected by ... in the screening of individuals at high-risk of developing pancreatic cancer. ...
-
Dr Frances Richards
-
Dr Giulia Biffi
-
Professor Duncan Jodrell
... with cancer with much of my effort now focussing on pancreatic cancer. An overview of pancreatic ductal adenocarcinoma and current drug treatment (presentation ...