Programme Members

Programme Contacts

University of Cambridge
Cancer Research UK Cambridge Institute
Cambridge University Hospitals NHS Foundation Trust, Papworth Hospital NHS Foundation Trust
Cancer Research UK Cambridge Institute
University of Cambridge
Department of Oncology, Department of Biochemistry
Programme Manager

Selected publications

Principal investigators and consultants

  • All members
  • Group leaders
  • Clinical consultants
Department of Pharmacology
CRUK Cambridge Institute
Molecular genetics of breast cancer
PI:
N
CC:
N
University of Cambridge
Department of Oncology
Strangeways Research Laboratory
Increased understanding of the genetic basis for the wide variation between patients in the severity of late radiotherapy toxicity.
PI:
N
CC:
I work on a novel organotypic in vitro model for squamous cell lung cancer. It models common early genetic lesions in an inducible system...
PI:
N
CC:
N
MRC Laboratory of Molecular Biology
Protein and Nucleic Acid Chemistry
Hyperactivation of the Wnt pathway has been linked to a wide range of cancers. Notably, the majority of colorectal cancers are due to...
PI:
Y
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Pathology
.
PI:
N
CC:
Y
Wellcome Trust Sanger Institute
Cancer Genome Project
My research focuses on the optimisation of forward genetic screens to model acquired drug resistance to targeted therapeutics and the...
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
Despite significant advances over the last decade in the adjuvant and neo-adjuvant treatment of colorectal cancer (CRC) disease relapse is...
PI:
Y
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Department of Oncology
My primary interest is working towards the better understanding of the biology of paediatric wild type GISTs. We have established a...
PI:
N
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N
Cambridge University Hospitals NHS Foundation Trust
Department of Medicine
Cambridge University Hospitals
I am interested in several aspects of GI cancer including aetiology, identification of high-risk individuals and techniques for earlier...
PI:
N
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Department of Medicine
My group is interested in the intracellular mechanisms regulating NADPH oxidase function in neutrophils and the control of neutrophil and...
PI:
Y
CC:
Y
University of Cambridge
Department of Physics
We are interested in understanding soft materials and open questions in cellular biology. There is a strong synergy between these two...
PI:
Y
CC:
N
Babraham Institute
Signalling Laboratory
In terms of basic science we are interested in how protein kinase and lipid signalling pathways control cell fate decisions such as...
PI:
Y
CC:
N
Clinical research in thoracic cancer with emphasis on surgery. Local PI for PULMICC study- a RCT of metastectomy v best other care for...
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Cambridge Colorectal Unit
Justin Davies Clinical Director of Digestive Diseases and Consultant Colorectal Surgeon at Addenbrooke's Hospital, and an Associate...
PI:
N
CC:
Y
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Department of Oncology
Cambridge University Hospitals NHS Foundation Trust
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Surgery
2009 Successful grant £20 000 from Addenbrookes Charitable Trust for research proposal: Anal cytology, anoscopy and human papillomavirus...
PI:
Y
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Department of Oncology
My research is based on improving outcomes of chemotherapy in oesophageal and gastric cancer. I am chief investigator of a national phase 3...
PI:
Y
CC:
Y
Wellcome Trust Sanger Institute
Wellcome Sanger Institute
Leads the effort to derive and characterise a large panel of cancer organoid models as part of the international Human Cancer Models...
PI:
N
CC:
N
AstraZeneca
Oncology iMED
Investigation of the therapeutic index of combining inhibitors of the DNA damage response with radiation in lung cancer.
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Oncology
David Gilligan is a Consultant Clinical Oncologist at Addenbrooke's and Papworth Hospitals in Cambridge. He is the Clinical Lead for Acute...
PI:
N
CC:
Y
University of Cambridge
Department of Oncology, Department of Biochemistry
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Surgery
Colorectal Unit
Nigel Hall is a Colorectal and General Surgeon at Addenbrooke's Hospital.  He is lead of the Colorectal Multidisciplinary Team and Deputy...
PI:
Y
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Department of Oncology
Dr Susan Harden is the Oncology Lead Clinician for Lung Cancer at Addenbrooke's hospital. She qualified in medicine from Oxford University...
PI:
Y
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Upper Gastrointestinal (GI) Unit
.
PI:
Y
CC:
Y
University of Cambridge
Department of Medicine
CRUK Cambridge Institute
Cambridge Hospitals NHS Foundation Trust
Cellular senescence and oncogene induced senescence in particular is a potent tumour suppressor mechanism. Hepatocytes from subjects with...
PI:
N
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Colorectal Unit
.
PI:
N
CC:
Y
Project leader with extensive experience in Oncology drug discovery and development, leading teams to translate pre-clinical candidate...
PI:
N
CC:
N
University of Cambridge
Department of Gynaecological Oncology
Homeostatic turnover in adult tissues is governed by the interplay of a multitude of signalling pathways that are often triggered by niche...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
My research is broadly in statistical questions arising from molecular biology, cancer genetics or cancer treatment. The four themes of my...
PI:
N
CC:
N
University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, Papworth Hospital NHS Foundation Trust
Department of Medicine
Cambridge Institute for Medical Research
Professor of Respiratory Science, Honorary Consultant Respiratory Physician
Proteins destined for secretion or for insertion into the cell membrane are first folded within the endoplasmic reticulum. The process of...
PI:
N
CC:
N
University of Cambridge
MRC Cancer Unit
Hutchison MRC Research Centre
Modelling tumour development and therapy The main aim of our programme is to define the molecular and functional alterations that enable...
PI:
Y
CC:
University of Cambridge
Department of Biochemistry, School of Clinical Medicine
Cambridge University Hospitals NHS Trust
My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and...
PI:
Y
CC:
Y
Wellcome Trust Sanger Institute
Cancer Genome Project
Advances in genome sequencing technologies are enabling researchers to make rapid progress in defining the entire repertoire of causal...
PI:
Y
CC:
Y
University of Cambridge
Hutchison MRC Research Centre
Histopathology Department, CUH
.
PI:
N
CC:
Y
University of Cambridge
Cancer Research UK Cambridge Institute
I am interested in the use of mathematical and computational approaches to understand the functioning of healthy adult stem cells and the...
PI:
N
CC:
N
Department of Oncology
CRUK Cambridge Institute
PI:
Y
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Histopathology
.
PI:
N
CC:
Y
University of Cambridge
Department of Genetics
Wellcome Trust MRC Cambridge Stem Cell Institute
My interest is in the characterisation of the biology of stem cells in normal lung and lung cancer, which should subsequently lead to an...
PI:
N
CC:
N
I am currently investigating the function of a Adnp, a novel interactor of the NuRD complex in embryonic stem cells.
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Wellcome Trust Sanger Institute
Department of Oncology
We use DNA sequencing of patients and their tumours to study genomic evolution in melanoma.
PI:
N
CC:
N
I am a bioinformatician working in the Experimental Cancer Genetics group at the Wellcome Trust Sanger Institute. My primary interest is to...
PI:
N
CC:
N
Papworth Hospital NHS Foundation Trust
Department of Pathology
.
PI:
N
CC:
Y
Department of Pathology
Wellcome Trust CRUK Gurdon Institute
The Rawlins lab works on the roles of stem cells in lung development and homeostasis with the dual aims of understanding how the normal...
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust, Papworth Hospital NHS Foundation Trust
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
Dr Rintoul's research is based around clinical trials and translational research in thoracic oncology. Currently he is the Chief...
PI:
Y
CC:
Y
Papworth Hospital NHS Foundation Trust
.
PI:
N
CC:
Y
Papworth Hospital NHS Foundation Trust
Department of Radiology
Dr Screaton was appointed Consultant Radiologist in Papworth and Addenbrooke's Hospitals, Cambridge in 2000. He specialises in...
PI:
N
CC:
Y
GlaxoSmithKline
Biopharm Innovation
PK, PD, systems biology
PI:
Y
CC:
N
(tbc)
PI:
N
CC:
N
University of Cambridge
MRC Cancer Unit
Hutchison MRC Research Centre
.
PI:
Y
CC:
University of Cambridge
Department of Public Health and Primary Care
PI:
N
CC:
AstraZeneca
Science lead on Selumetinib (MEK inhibitor) and AZD4547 (FGFR tyrosine kinase inhibitor) • Bioscience representative on the licensing...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
The role of Myc in pancreatic cancer and the tumor microenvironment
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Surgery
Received a MD in surgical oncology. Worked under the supervision of Professor Mark Middleton and Len Seymour in Oxford looking into...
PI:
N
CC:
Y
Cambridge University Hospitals NHS Foundation Trust
Colorectal Unit
.
PI:
N
CC:
Y