Programme Members

Programme Contacts

University of Cambridge
Department of Biochemistry
Programme Lead
University of Cambridge
Department of Pathology
Programme Lead
University of Cambridge
Department of Biochemistry
Co-Training Lead
University of Cambridge
Department of Pathology, Department of Genetics
Co-Training Lead
University of Cambridge
Department of Oncology, Cancer Research UK Cambridge Institute
Programme Manager
  • All members
  • Group leaders
  • Clinical consultants
MRC Laboratory of Molecular Biology
Cancer Research UK Cambridge Institute
PI:
N
CC:
N
Wellcome Trust Sanger Institute
Not applicable/other
Mouse Genomes Project
David performs forward genetic screens to uncover cancer genes and pathways and leads a programme to decode the genomes of several mouse...
PI:
Y
CC:
N
University of Cambridge
Wellcome Trust CRUK Gurdon Institute
Wellcome Trust CRUK Gurdon Institute
We investigate the functions chromatin regulatory complexes implicated in human disease using the C. elegans model system. These include...
PI:
Y
CC:
N
University of Cambridge, Cambridge University Hospitals NHS Foundation Trust
Cancer Research UK Cambridge Institute, Not applicable/other
MRC Toxicology Unit; Cambridge University Hospitals NHS Foundation Trust
PI:
Y
CC:
Y
Ubiquitin-mediated signaling in cell division
PI:
N
CC:
N
MRC Laboratory of Molecular Biology
Not applicable/other
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry, Department of Pharmacology, Department of Oncology
Rotation Project: The project aims to investigate the cellular role(s) of a novel factor expected to be involved in DNA damage response....
PI:
N
CC:
N
Babraham Institute
Role of MAPK in cancer cell survival signalling
PI:
N
CC:
University of Cambridge
Department of Pathology
Wellcome Trust CRUK Gurdon Institute
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My...
PI:
N
CC:
N
Other
Department of Physiology, Development and Neuroscience, Wellcome Trust CRUK Gurdon Institute
Wellcome Trust CRUK Gurdon Institute
An understanding of the diversity of neural progenitors and flexibility in their fate choices - lineage plasticity - is crucial for...
PI:
Y
CC:
N
University of Cambridge
Department of Chemistry
Unilever Centre for Molecular Science Informatics
Previously affiliated with the Lead Discovery Informatics (LDI) group of Novartis in Cambridge/MA, I am now developing and applying...
PI:
Y
CC:
N
MRC Laboratory of Molecular Biology
Not applicable/other
Protein and Nucleic Acid Chemistry Division
Hyperactivation of the Wnt pathway has been linked to a wide range of cancers. Notably, the majority of colorectal cancers are due to...
PI:
Y
CC:
N
University of Cambridge
Department of Pathology
PI:
N
CC:
N
University of Cambridge
Department of Pathology, Department of Genetics
My group develops new computational methods to study how dysregulation and errors in DNA replication and mitosis lead to genome instability...
PI:
Y
CC:
N
University of Cambridge
Department of Chemistry
The aim of my research is to build ruthenium organometallic groups into validated, medicinal compounds such that the ligand efficiency of...
PI:
Y
CC:
N
University of Cambridge
Department of Physiology, Development and Neuroscience
Wellcome Trust CRUK Gurdon Institute
PI:
Y
CC:
N
University of Cambridge
Department of Physiology, Development and Neuroscience
In many cancers unchecked proliferation is driven by inappropriate activity of signalling pathways, such as the Notch pathway. Activation...
PI:
Y
CC:
N
European Bioinformatics Institute
Not applicable/other
Functional genomics research
High throughput (microarray, sequencing) data analysis. Data integration. Cell cycle. I am in charge of running and developing the...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
I work on the development of new technologies for the spatial and temporal control of biological events in vivo. Specifically, I am using...
PI:
N
CC:
N
CRUK Therapeutic Discovery Laboratories
Not applicable/other
Drug discovery at CRT working in medicinal chemistry to deliver small molecule inhibitors of cancer targets.
PI:
N
CC:
N
AstraZeneca
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Clinical Biochemistry
Cambridge Institute for Medical Research
Our work aims to determine of the cellular role(s) of myosin motor proteins in intracellular transport processes, cell signaling and...
PI:
Y
CC:
N
AstraZeneca
Primary research interests include ChIP-seq and integrative ChIP-seq/expression analysis.
PI:
N
CC:
University of Cambridge
Department of Materials Science and Metallurgy
My research concerns medical materials. We design, produce and characterise materials designed for use within the body, materials for...
PI:
Y
CC:
N
AstraZeneca
Not applicable/other
Translational Science - Oncology Innovative Medicines Unit
Applying cutting edge genomic techniques to measure biomarkers and further understanding of response and resistance across a range of drug...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
Biology of Ras-induced senescence
PI:
N
CC:
N
University of Cambridge
Department of Chemistry
CRUK Cambridge Institute
Yuqi Chen
PI:
N
CC:
N
Babraham Institute
Not applicable/other
How do the cells of an organism, all of which have exactly the same genetic code, adopt such different fates, morphologies and functions?...
PI:
Y
CC:
N
Wellcome Trust Sanger Institute
Not applicable/other
PI:
Y
CC:
N
University of Cambridge
Department of Medicine
PI:
N
CC:
N
Babraham Institute
Not applicable/other
Signalling Laboratory
In terms of basic science we are interested in how protein kinase and lipid signalling pathways control cell fate decisions such as...
PI:
Y
CC:
N
AstraZeneca, MedImmune
Not applicable/other
CRUK Cambridge Institute
AstraZeneca Oncology
Oncology
PI:
N
CC:
N
We aim to understand the molecular basis of chromosome stability in human cells. Genetic predisposition to cancer is commonly precipitated...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
PI:
N
CC:
N
University of Cambridge
Department of Pathology
Defects in cell division often cause abnormal distribution of the genetic material between the two daughter cells. These abnormalities...
PI:
Y
CC:
N
University of Cambridge
Department of Oncology
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
The molecular aetiology of colorectal cancer (CRC) is well known: the mutant, oncogenic form of the Wnt signaling pathway drives the...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
DNA repair and DNA damage signalling The main focus of research in our lab is to better understand how cells detect DNA damage and signal...
PI:
N
CC:
Other
Not applicable/other
TBC(test account for DC Systems - do not delete, just set status to Blocked)
PI:
N
CC:
N
Babraham Institute
Signalling
I study entosis, a recently described process of live epithelial cell engulfment which occurs in human tumours. My work aims to identify...
PI:
N
CC:
N
AstraZeneca, Babraham Institute, University of Cambridge
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Cambridge Institute for Medical Research, Department of Medicine
Cambridge Institute for Medical Research
Within the Marciniak lab, we work to identify new targets and therapeutic strategies for the treatment of mesothelioma.We work in...
PI:
N
CC:
N
University of Cambridge
Department of Genetics
I am interested in chromosome biology and the relationship between the structural organisation of vertebrate chromosomes and their function...
PI:
Y
CC:
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Department of Oncology
Department of Medical Oncology, Addenbrooke's Hospital, Cambridge; Department of Oncology, Queen Elizabeth Hospital King's Lynn, King's Lynn.
PI:
N
CC:
N
University of Cambridge
Department of Pathology
PI:
Y
CC:
N
University of Cambridge
Department of Chemistry
-
PI:
Y
CC:
MRC Laboratory of Molecular Biology
Protein and Nucleic Acid Chemistry (PNAC)
Structural and functional analysis of Wnt pathway components
PI:
N
CC:
University of Cambridge
Department of Physiology, Development and Neuroscience
Primordial germ cells (PGCs) are the cells that go on to become sperm or eggs in the adult organism. During embryonic development,...
PI:
N
CC:
N
AstraZeneca
Not applicable/other
UK trained Clinical Oncologist PhD in Oncology - Vascular Targeting Agents - endothelial cell shape change effects and translational...
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
Wellcome Trust CRUK Gurdon Institute
We are interested in understanding the mechanisms underlying remodelling of the actin cytoskeleton. Force generation by actin...
PI:
Y
CC:
University of Cambridge
Department of Pathology
PI:
Y
CC:
N
University of Cambridge
Department of Astronomy
My group focuses on nonequilibrium phenomena in the natural world, with particular emphasis on biological physics. We strive for a holistic...
PI:
Y
CC:
University of Cambridge
Department of Chemistry
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
Science Communication Specialist, Cell and Molecular Biology Programme
PI:
N
CC:
N
University of Cambridge
Cambridge Institute for Medical Research
Cambridge Institute for Medical Research
PI:
Y
CC:
N
Wellcome Trust Sanger Institute
Department of Medicine
Honorary clinical fellow, CUH NHS Trust
I am an early-career medical oncologist from Melbourne, Australia. I am broadly interested in immuno-oncology and the link between cancer...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
I am a PhD student in the Department of Biochemistry on the Cancer Research UK Cambridge Centre’s MRes/PhD training programme. I completed...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
(tbc)
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
PI:
N
CC:
N
AstraZeneca
Not applicable/other
Director, translational science "
Head of department for UK translational science, oncology, AstraZeneca
PI:
N
CC:
N
CRUK Therapeutic Discovery Laboratories
Not applicable/other
Rebecca is a Group Leader within Biosciences at Cancer Research Horizons. She was formerly Head of Target Discovery at the Milner...
PI:
Y
CC:
N
Babraham Institute
I have a long term interest in the PI3K signalling system and how it operates as a key signal integrator in a range of signallling networks...
PI:
Y
CC:
N
University of Cambridge
Wellcome Trust MRC Cambridge Stem Cell Institute, Department of Biochemistry
PI:
Y
CC:
N
University of Cambridge, Cambridge University Hospitals NHS Foundation Trust
Department of Physiology, Development and Neuroscience
Clinical School University of Cambridge
PI:
N
CC:
N
GlaxoSmithKline
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
I'm a PhD student on CRUK Cambridge Centre's MRes+PhD Programme based in the Department of Biochemistry. My research is aligned to the Cell...
PI:
N
CC:
N
Babraham Institute
Not applicable/other
We study mechanisms by which cells learn to thrive in new environments. From yeast scattered across the landscape to malignant cells facing...
PI:
Y
CC:
N
Other
Not applicable/other
david howe
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
Linda
PI:
N
CC:
N
Department of Veterinary Medicine
I study the mammary gland and tumours developing in this tissue. My particular field of interest encompasses the interactions between...
PI:
Y
CC:
N
We are using fragment based drug discovery methods to target a traditionally difficult class of drug targets, with emphasis on inhibition...
PI:
N
CC:
N
University of Cambridge
Department of Genetics
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
Cancer development and epigenetic change, especially related to imprinting.
PI:
N
CC:
N
University of Cambridge
Department of Pharmacology
Our research focuses on a class of proteins known as tandem-repeat proteins such as ankyrin, tetratricopeptide and leucine-rich repeats....
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
Proteomic approaches to plasma-membrane assemblies: Membrane proteins cluster together selectively as spatially-restricted, functionally...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute, Department of Biochemistry
CRUK Cambridge Institute
None
The main focus of research in our lab is to better understand how cells detect DNA damage and signal its presence to the DNA repair,...
PI:
Y
CC:
N
University of Cambridge
Department of Medical Genetics
PI:
N
CC:
Y
CRUK-AstraZeneca Antibody Alliance Laboratory
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Wellcome Trust CRUK Gurdon Institute, Department of Physiology, Development and Neuroscience
Wellcome Trust CRUK Gurdon Institute
I am concentrating on promoting developmental mechanics and microrobotic engineering, aiming at developing interdisciplinary paradigms to...
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
PI:
N
CC:
N
We work on how the body responds to hypoxia, or low levels of tissue oxygen.  This is relevant to a number of diseases, including cancer,...
PI:
Y
CC:
N
CRUK Therapeutic Discovery Laboratories
Department of Engineering
Discovery Bioscience
I am a senior group leader at Cancer Research Technology Discovery Laboratories [CRTDL] (a wholly owned subsidiary of Cancer Research UK)....
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
MRC Cancer Unit
PI:
N
CC:
N
University of Cambridge
Department of Pharmacology
PI:
N
CC:
N
Department of Physiology, Development and Neuroscience
Wellcome Trust CRUK Gurdon Institute
PI:
N
CC:
N
University of Cambridge
Department of Engineering
My main research activities focus on the mechanical properties of soft disordered materials, including foams, granular materials, as well...
PI:
Y
CC:
University of Cambridge
Department of Surgery
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
Wellcome Trust CRUK Gurdon Institute
PI:
N
CC:
N
Genestack Limited
Not applicable/other
Genestack Limited
Genestack was launched in 2012 with a mission to transform genomics big data computing and application engineering. We were founded by...
PI:
N
CC:
MRC Laboratory of Molecular Biology
Conserved mechanisms in chemotaxis. How cells sense and move in chemical gradients; how they make projections - pseudopodia and blebs -...
PI:
Y
CC:
MRC Laboratory of Molecular Biology
Not applicable/other
PI:
N
CC:
N
Biology of MHC class I and class II antigen processing and presentation pathways.
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
PI:
Y
CC:
N
CRUK Therapeutic Discovery Laboratories
Not applicable/other
The application of Medicinal Chemistry to the design and development of anti-cancer agents.
PI:
N
CC:
University of Cambridge
Department of Biochemistry
We are interested in understanding of the links between deficiencies in the DNA damage response and the molecular nature of disease....
PI:
Y
CC:
N
Babraham Institute
PI:
Y
CC:
N
Babraham Institute
Not applicable/other
PI:
N
CC:
N
Department of Computer Laboratory
I conduct research in computer science - in natural language processing and text mining. I have research projects which focus on biomedical...
PI:
Y
CC:
University of Cambridge
Department of Biochemistry
Mechanisms and models of cancer.
PI:
N
CC:
N
University of Cambridge
Milner Therapeutics Institute, Wellcome Trust CRUK Gurdon Institute
Tony Kouzarides is Professor of Cancer Biology at the University of Cambridge, Deputy Director of the Gurdon Institute and Director of the...
PI:
Y
CC:
N
University of Cambridge
Department of Zoology
For a cell to proliferate in cancer, and during normal development or tissue maintenance, it must replicate its chromosomal DNA. We are...
PI:
Y
CC:
University of Cambridge
Department of Haematology
Wellcome Trust MRC Cambridge Stem Cell Institute
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
University of Cambridge
The study of the structure and function of protein complexes, mainly using either NMR spectroscopy or X-ray crystallography, but also...
PI:
Y
CC:
University of Cambridge
Department of Medicine
Cambridge Institute for Medical Research
We study MHC I molecules and other critical cell surface receptors. We showed that the cancer-causing herpesviruses (KSHV) pirated...
PI:
Y
CC:
University of Cambridge
Department of Chemistry
PI:
Y
CC:
University of Cambridge
Department of Chemistry
Centre for Applied Medical Statistics
later on
PI:
N
CC:
University of Cambridge
Department of Medicine
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
Milner Therapeutics Institute
The research carried out in the Cambridge Centre for Proteomics centres around three main areas: ? Development of quantitative proteomics...
PI:
Y
CC:
My lab studies cell division in human cells, with particular focus on regulation by ubiquitin-mediated proteolysis. We use time-lapse...
PI:
Y
CC:
N
University of Cambridge
Department of Computer Laboratory
I am interested in developing and testing artificial intelligence and modeling methodologies for healthcare.
PI:
Y
CC:
Other
Department of Pathology
We are focussed on understanding the biology of regulatory T cells within the tissues. How they migrate there, what controls their numbers...
PI:
Y
CC:
N
University of Cambridge
Department of Biochemistry
The use of classical, germ-line genetics to define gene function in vertebrates is severely limited by embryonic lethality, developmental...
PI:
Y
CC:
University of Cambridge
Department of Medicine
PI:
Y
CC:
N
Babraham Institute
Not applicable/other
Signalling Programme
All living cells constantly sense and respond to their environment. Inside the cell, there is a complex network of signalling pathways,...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
I study the processes involved in DNA replication in eukaryotes, including the mechanism of priming by the replicative primase and the...
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Department of Medicine, Wellcome Trust MRC Cambridge Stem Cell Institute
Wellcome Trust MRC Cambridge Stem Cell Institute
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
PI:
Y
CC:
N
University of Cambridge
Not applicable/other
Milner Therapeutics Institute
PI:
N
CC:
N
Babraham Institute, CRUK Therapeutic Discovery Laboratories, University of Cambridge
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Wellcome Trust MRC Cambridge Stem Cell Institute
Wellcome Trust MRC Cambridge Stem Cell Institute, CRUK Cambridge Institute
PI:
N
CC:
N
University of Cambridge
Department of Zoology
Wellcome Trust CRUK Gurdon Institute
I am interested in the role played by two S/T protein kinases in mitosis (Aurora A and Cdk1). Both of them have several key roles at...
PI:
N
CC:
AstraZeneca, University of Cambridge
Department of Biochemistry
PI:
N
CC:
N
Babraham Institute
Not applicable/other
Alterations in intercellular signalling pathways are often the initiating event in carcinogenesis. A prime example being...
PI:
Y
CC:
N
MRC Laboratory of Molecular Biology
Not applicable/other
I have expertise in a wide range of biophysical techniques to characterise protein-protein and protein-ligand interactions to understand...
PI:
N
CC:
Wellcome Trust Sanger Institute
Not applicable/other
Addenbrooke's Hospital, CUH NHS Foundation Trust
PI:
N
CC:
N
Other
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
Wellcome Trust CRUK Gurdon Institute
Our main goal is to understand how cells interpret genetic and epigenetic information as well as environmental cues to determine their...
PI:
Y
CC:
Sareum Ltd
Not applicable/other
Sareum Ltd
Sareum is a drug discovery and development company delivering targeted small molecule therapeutics, primarily focusing on cancer. Sareum...
PI:
Y
CC:
Metabolic response of the cells adapts to proliferation requirements indicating that there is a cross talk between cell cycle and metabolic...
PI:
Y
CC:
N
European Bioinformatics Institute, University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
My primary research focus is the development and application of computational algorithms to uncover how cells respond to their enviroment,...
PI:
Y
CC:
N
University of Cambridge
Department of Physics
We are a small, highly interactive and international research team whose passion is using new technological innovations to improve our...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
Small G proteins are molecular switches in cellular signal transduction. Many small G proteins that we are studying, such as Ras and Ral,...
PI:
Y
CC:
University of Cambridge
Department of Clinical Neuroscience
PI:
N
CC:
N
University of Cambridge
Department of Veterinary Medicine
Elizabeth Murchison studies the genetics and evolution of clonally transmissible cancers. Transmissible cancers are unusual cancers that...
PI:
Y
CC:
N
University of Cambridge
Department of Chemistry
University of Cambridge
Involved in the chemical synthesis of novel agents.
PI:
Y
CC:
European Bioinformatics Institute, Wellcome Trust Sanger Institute
Not applicable/other
Open Targets Postdoctoral Fellow responsible for the development of new algorithms and computational tools for scoring cancer in vitro...
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
cellular senescence
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
To understand mechanisms of cellular response to the stresses, such as cellular senescence and apoptosis.
PI:
Y
CC:
N
University of Cambridge
Department of Medicine
Cambridge Institute for Medical Research
Cambridge Institute for Therapeutic Immunology and Infectious Disease
Cellular mechanisms of oxygen and metabolite sensing: A fundamental requirement for cell survival is the ability to respond to local...
PI:
Y
CC:
Y
Other
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Not applicable/other
Computer Laboratory
I am a Mathematician and I am doing a PhD in bioinformatics at the University if Cambridge. I am currently working on gene network...
PI:
N
CC:
N
Babraham Institute
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
Our goal is to understand the systems-level transcriptional mechanisms underlying mammalian cell specification, which are often perturbed...
PI:
Y
CC:
Other
Not applicable/other
PI:
N
CC:
AstraZeneca, University of Cambridge
Department of Biochemistry, Department of Genetics, Wellcome Trust MRC Cambridge Stem Cell Institute
Wellcome Trust MRC Cambridge Stem Cell Institute
PI:
N
CC:
N
MRC Laboratory of Molecular Biology, University of Cambridge
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
Our work focuses on the relationship between structure and function in small G proteins and their effectors and regulators. These proteins...
PI:
Y
CC:
University of Cambridge
Department of Biochemistry
PI:
N
CC:
N
MRC Laboratory of Molecular Biology
Not applicable/other
Structural Studies
We use a hybrid approach to study the structure and function of multi-protein complexes. A major focus of the lab is on complexes involved...
PI:
Y
CC:
University of Cambridge
MRC Cancer Unit
Hutchison MRC Research Centre
My work focuses on understanding the transcriptional dependencies of renal cancer cells using state-of-the-art techniques including CRISPR-...
PI:
N
CC:
N
University of Cambridge
MRC Cancer Unit
Hutchison MRC Research Centre
Khushali Patel
PI:
N
CC:
N
University of Cambridge
Department of Chemistry
Organic synthesis - generally related to anticancer natural products and analogues. Synthesis of potent cytotoxic payloads for antibody-...
PI:
Y
CC:
University of Cambridge, Other
Department of Biochemistry
Luca's research focuses on the relationship between cancers and physiological but not homeostatic processes like tissue regeneration and...
PI:
N
CC:
N
University of Cambridge
Department of Biochemistry
The faithful inheritance of genetic information is essential to cellular life. Successful transmission of the genetic material requires the...
PI:
Y
CC:
My main interest is understanding what is behind the heterogeneity of breast cancer. Through the identification of cell fate regulators in...
PI:
N
CC:
N
University of Cambridge
Department of Chemical Engineering and Biotechnology
PI:
N
CC:
N
University of Cambridge
Department of Haematology
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Wellcome Trust Sanger Institute
Department of Oncology
We use DNA sequencing of patients and their tumours to study genomic evolution in melanoma.
PI:
N
CC:
N
Wellcome Trust Sanger Institute
Not applicable/other
PI:
N
CC:
N
Babraham Institute, University of Cambridge
Department of Biochemistry
PI:
N
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
PI:
Y
CC:
N
University of Cambridge
MRC Cancer Unit
Aisling received her undergraduate degree in Genetics from Trinity College Dublin and PhD from Dublin City University. She completed...
PI:
N
CC:
N
Babraham Institute
Not applicable/other
B-lymphocytes are cells of the immune system responsible for the production of antibodies, and do so by employing hazardous mechanisms of...
PI:
Y
CC:
N
University of Cambridge
Department of Physiology, Development and Neuroscience
PI:
Y
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Pathology
The adaptive immune system employs a variety of suppressive mechanisms, collectively referred to as immunoregulatory mechanisms, to...
PI:
Y
CC:
N
Department of Medical Genetics
Cambridge Institute for Medical Research
PI:
Y
CC:
N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
Alasdair heads up a specialised team that provide a centralised ‘Hub’ for the innovation and application of state-of-the-art Genome Editing...
PI:
N
CC:
N
MRC Laboratory of Molecular Biology
My lab is interested in the mechanisms that alleviate arrested DNA replication and the impact their loss has on mutagenesis and on the...
PI:
Y
CC:
N
Babraham Institute
Not applicable/other
My lab at the Babraham Institute is probing how different protein clearance pathways--with a focus on the ubiquitin-proteasome system and...
PI:
Y
CC:
N
University of Cambridge
Department of Genetics
The molecular mechanisms by which chromatin exerts control over stress response is the main focus of the Unit programme. We aim to address...
PI:
Y
CC:
N
University of Cambridge
Not applicable/other
Wellcome Trust CRUK Gurdon Institute
PI:
N
CC:
N
University of Cambridge
MRC Cancer Unit
Hutchison MRC Research Centre
My research focuses on the role of metabolic reprogramming during transformation and tumour evolution. We are interested in kidney cancer...
PI:
N
CC:
N
Cambridge University Hospitals NHS Foundation Trust
Department of Radiology
PI:
N
CC:
Y
University of Cambridge
Department of Genetics
Spindle morphogenesis is regulated by cyclin-dependent kinases (CDKs) and monitored by checkpoints to enforce accurate chromosomal...
PI:
Y
CC:
Babraham Institute
Not applicable/other
Our aim is to understand the function and regulation of receptor tyrosine phosphatases in vivo using proteomics, cell biology and mouse...
PI:
Y
CC:
N
Other
Not applicable/other
Milner Therapeutics Institute
PI:
N
CC:
N
Other
Not applicable/other
PI:
N
CC:
N
University of Cambridge
Department of Physics
I'm programme co-ordinator for www.voxtox.org and www.accel-rt.org, two interdisciplinary computational radiotherapy research programmes.
PI:
N
CC:
Cambridge University Hospitals NHS Foundation Trust, European Bioinformatics Institute, University of Cambridge
Department of Pathology
Depts. Dermatology and Clinical Pharmacology
I am a clinician scientist based in Cambridge. My research is focused on using cutting edge computational and mathematical tools to...
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Y
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N
University of Cambridge
Department of Chemistry
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N
University of Cambridge
Department of Chemistry
Our research interests are centered on using organic synthesis to make small molecules and peptides, which potentially could be used for...
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Y
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University of Cambridge
Department of Pharmacology
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Y
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N
University of Cambridge
Department of Genetics
Wellcome Trust CRUK Gurdon Institute
Most tumours arise from epithelial tissues composed of polarised cells that stick together to form sheets, and a loss of polarity is a...
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Y
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European Bioinformatics Institute
Not applicable/other
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N
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N
MRC Laboratory of Molecular Biology
Nuclear trafficking and structural cell biology
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Y
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University of Cambridge
Department of Clinical Neuroscience
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N
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N
University of Cambridge
Department of Engineering
I am interested in developing engineering materials models for soft tissue in collaboration with medical researchers and clinicians and...
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Y
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University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
I am spearheading a translational research initiative focused on developing circulating tumour DNA (ctDNA) based biomarkers derived from...
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Y
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N
University of Cambridge
Department of Biochemistry
Wellcome Trust CRUK Gurdon Institute
We study epigenetic pathways and the mechanisms through which these processes are corrupted by disease-associated mutations in chromatin...
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N
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N
Wellcome Trust Sanger Institute
Not applicable/other
Addenbrookes Hospital
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University of Cambridge
Department of Medicine
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Y
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Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Department of Surgery
CRUK Cambridge Institute
CUH NHS
I am Isaac, an MRes + PhD student studying with the Cancer Research UK Cambridge Centre. My MRes rotations focused on immuno-oncology,...
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N
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N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
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Y
CC:
N
University of Cambridge
Department of Oncology, Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
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N
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N
University of Cambridge
Department of Pathology
Cambridge Institute for Medical Research
Immunogenetics and functions of the MHC Immunogenetics of NK receptors and related molecules
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Y
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N
University of Cambridge
Not applicable/other
Milner Therapeutics Institute
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Babraham Institute, University of Cambridge
Not applicable/other
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N
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N
University of Cambridge
Department of Veterinary Medicine
Single cell/Tissue imaging, quantitative microscopy, image analysis 
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N
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N
Cambridge University Hospitals NHS Foundation Trust
Not applicable/other
Wellcome Trust CRUK Gurdon Institute
PI:
N
CC:
Y
University of Cambridge
Department of Pharmacology
Our research focusses on molecular mechanisms of multidrug transport proteins that efflux cytotoxic drugs away from their intracellular...
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Y
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N
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Royal Papworth Hospital NHS Foundation Trust
Cambridge Institute for Medical Research
Cambridge Institute for Medical Research
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N
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N
MRC Laboratory of Molecular Biology
Medical Research Council Laboratory of Molecular Biology
We work on the aggregation mechanism of the tumor suppressor protein, p53, and developing novel anti-cancer drugs that function by...
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N
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N
University of Cambridge
Department of Pathology
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N
CC:
N
MRC Laboratory of Molecular Biology
Laboratory of Molecular Biology
Many signal transduction pathways cells involve enzymes that generate either soluble or membrane-resident second messengers by modifying...
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Y
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University of Cambridge, Other
Not applicable/other
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N
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N
University of Cambridge
Department of Biochemistry, Department of Pharmacology
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Y
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N
University of Cambridge
Wellcome Trust CRUK Gurdon Institute, Department of Physiology, Development and Neuroscience
Wellcome Trust CRUK Gurdon Institute
PI:
Y
CC:
N
University of Cambridge
Department of Pathology
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N
CC:
N
University of Cambridge
Department of Biochemistry
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N
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N
Other
Department of Clinical Biochemistry
CRUK Cambridge Institute, Cambridge Institute for Medical Research
My project focuses on understanding the role of the putative tumour suppressor PTPRK in colorectal cancer. PTPRK is a cell surface protein...
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N
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N
University of Cambridge
Cancer Research UK Cambridge Institute
CRUK Cambridge Institute
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N
CC:
N
University of Cambridge
Department of Genetics
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N
CC:
N
University of Cambridge
Wellcome Trust CRUK Gurdon Institute
The Regulation of Replication Initiation in Eukaryotes Faithful inheritance of the genome from mother to daughter cell requires that it is...
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Y
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N
University of Cambridge
Cambridge Institute for Medical Research
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N
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University of Cambridge
Department of Pharmacology
HOW TRANSCRIPTIONAL REGULATORS CONTROL GENE EXPRESSION PROGRAMS AND CELL FATE IN NORMAL AND MALIGNANT CELLSHow the transcriptional...
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Y
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N