| ASCL1 and its interactors in neuroblastoma differentiation. |
Prof Anna Philpott |
Cambridge Stem Cell Institute |
| Characterisation of two newly discovered ASXL-related proteins: effects on chromatin structure. |
Prof. Andrew Firth |
Dept of Pathology |
| Characterization of primate-specific systems regulating aspects of the DNA damage response. |
Dr Michael Imbeault |
Dept of Genetics |
| Combinatorial targeting of anaplastic lymphoma kinase (ALK) signalling to treat cancer and obesity |
Dr Florian Merkle |
Dept of Clinical Biochemistry (Institute of Metabolic Science) |
| Determining the role and potential therapeutic targeting of aberrant fatty acid metabolism in lymphoma. |
Prof Brian Huntly |
Cambridge Stem Cell Institute (Haematology) |
| Development and testing of next generation oncolytic vaccinia viruses. |
Dr Brian Ferguson |
Dept of Pathology |
| Do small cell lung cancers exploit developmental mechanisms? * |
Dr Emma Rawlins |
Dept of Physiology, Development and Neuroscience |
| Elucidating the role of Micropeptides in B cell lymphoma. * |
Dr Dan Hodson |
Cambridge Stem Cell Institute (Haematology) |
| Engineering AI to map broken and repaired DNA during genome replication. |
Dr Michael Boemo |
Dept of Pathology |
| Exploring VHL-independent regulatory mechanism(s) of HIF for therapeutic benefit. |
Prof Margaret Ashcroft |
Dept of Medicine |
| Genetic interrogation of histone lysine demethylation by UTX. * |
Dr Iva Tchasovnikarova |
Dept of Biochemistry |
| Hamlet.rt Collect: Use of 3D epithelioid models to improve survival from head and neck cancer. * |
Dr Gillian C Barnett |
Dept. of Oncology |
| How do Leukaemia Mutations Alter Tissue Dynamics of Blood Stem / Progenitor Cells? |
Prof Bertie Gottgens |
Cambridge Stem Cell Institute (Haematology) |
| Human ultra-high field (7T) deuterium metabolic imaging. * |
Prof Chris Rodgers |
Dept of Clinical Neurosciences (Wolfson Brain Imaging Centre) |
| Investigating the role of cell migration in the pathogenesis of extragonadal germ cell tumours. |
Prof Ewa Paluch |
Dept of Physiology, Development and Neuroscience |
| Investigating the role of immune cell-mediated steroidogenesis in regulating cancer inflammation and immunity. |
Dr Bidesh Mahata |
Dept of Pathology |
| Machine learning and integrative ‘omics for multi-cancer risk prediction. |
Dr Siddhartha Kar |
Dept. of Oncology |
| Molecular mechanisms of DNA repair and replication in health and disease. |
Dr Luca Pellegrini |
Dept of Biochemistry |
| MYC translocation in aggressive B-cell lymphomas: why partner matters? * |
Prof. Ming Qing Du |
Dept of Pathology |
| Post-transcriptional regulation of Aurora kinase in the cell cycle and cancer. |
Dr Catherine Lindon |
Dept of Pharmacology |
| T cell synergy in anti-tumour responses. * |
Dr Arianne Richard |
Babraham Institute |
| Telomere maintenance, ageing and leukaemia prevention. |
Prof George Vassiliou |
Cambridge Stem Cell Institute (Haematology) |
| The impact of age, parity and germline mutations on mammary gland development at the single cell level. * |
Dr Walid Khaled |
Cambridge Stem Cell Institute (Pharmacology) |
| The role and regulation of membrane electric potential in migratory cells. |
Dr Fengzhu Xiong |
Dept of Physiology, Development and Neuroscience |
| Innate immune control of kidney cancer * |
Prof James Nathan |
Dept of Medicine |
| Mechanomodulation of mutant clonal competition; relevance for early tumour formation |
Dr Maria Alcolea |
Dept of Physiology, Development and Neuroscience |
| Impact of trisomy 21 on the dynamics of human foetal haematopoiesis and leukaemia predisposition |
Prof Elisa Laurenti |
Cambridge Stem Cell Institute (Haematology) |
