These are the trials that are currently open in the Early Phase trials team (Last updated 15 August 2019).
| Trial Short Name | Molecular Target(s) | Patient Population | Lead Investigator(s) in Cambridge |
| AZD1390 | ATM with RT | Glioblastoma | S Jeffries / R Baird |
| Basket of Baskets | PD-L1 | Solid tumours with high mutational load/MSI | R Baird |
| CALIBRATE | cfDNA evaluation | Patients on early phase clinical trials | R Baird / S Pacey |
| CALIBRATION | ctDNA evaluation | Advanced oesophageal malignancies | S Pacey |
| CamBMT1 phase II | EGFR/HER2 | Operable brain metastasis (breast/lung) | R Baird |
| CT7001 | CDK7 | Metastatic or locally advanced triple-negative breast cancer | R Baird |
| GO40782 | NTRK1/2/3 | Proven NTRK1/2/3 gene rearrangements | S Pacey |
| iBET | Bromodomain | Haematologic malignancies | B Huntly |
| LEAP-005 | PD-1 & RTK | Advanced TNBC, ovarian cancer, gastric cancer, GBM or BTC | B Basu |
| ONX-0801 | α-folate receptor | Platinum resistant ovarian cancer | B Basu |
| OUTREACH | CEBPα | Hepatocellular carcinoma | B Basu |
| PATRIOT | ATR | Any tumour type – palliative radiotherapy combined with ATR inhibitor | R Baird |
| POSEIDON phase II | PI3K | HR+ metastatic breast cancer | R Baird |
| MOv18 igE | α-folate receptor | Gyane aFR+ | B Basu |
| BOSTON | Mps1 | Advanced nonhaematological malignancies | B Basu |
| MP0274 | HER2 | HER2+ solid tumours | R Baird |
| AZD6738 | ATR | Solid tumours | D Jodrell |
| AZD9833 | HER2 | ER+ HER2- advanced breast cancer | R Baird |
| PARADIGM-2 | PARP | Glioblastoma | S Jefferies/ R Baird |