Cancer Molecular Diagnostics Laboratory

Facilitating translational research studies
and clinical trials to GCLP standard,
to ensure patient safety,
data accuracy and reliability.

About us

The Cancer Molecular Diagnostics Laboratory (CMDL) is part of the University of Cambridge School of Clinical Medicine Dept. of Oncology, located on the Cambridge Biomedical Campus.

The laboratory is jointly funded by the Cancer Research UK Cambridge Centre and the NIHR Cambridge Biomedical Research Centre.

The laboratory currently operates under Good Clinical Practice (GCP) and Good Clinical Lab Practice (GCLP) standards while working towards ISO 15189 accreditation.

CMDL services
  • Processing of patient samples
  • Extractions
  • Next-Generation Sequencing (NGS)
  • Specialised molecular assays
  • Bioinformatic analysis and data reporting

CMDL services are available to clinical trials and independent research groups.

Please contact us using the email address on the right, or click below for more about our services.

Clinical trials, translational and research studies

CMDL are involved in a many ongoing CTIMP and observational clinical trials as well as smaller translational and research studies, acting as a site, central laboratory, and contract researcher.

CMDL provide a spectrum of services to support the required endpoints and liaise directly with clinical teams to provide advice and support for trial/study setup and running.

Participation in External Quality Schemes

CMDL participates in the following Genomic Quality Assessment (GenQA)(EQA)/Proficiency Testing:  

  • BRCA testing for ovarian and prostate cancer (somatic)
  • Breast cancer PIK3CA testing
  • Chronic lymphocytic leukaemia (CLL) TP53 testing
  • Colorectal cancer (core)
  • DNA extraction from formalin-fixed paraffin embedded (FFPE) tissue
  • DNA extraction from fresh frozen tissue
  • DNA quantification
  • Gastrointestinal stromal tumours (GIST)
  • Lung cancer - EGFR only
  • Melanoma
  • Next Generation Sequencing (NGS) somatic - tumour testing only
  • Pathology of haematological neoplasm variants (classification only, pilot)
  • Pathogenicity of somatic sequence variants (pilot)

Cancer Molecular Diagnostics Laboratory, University of Cambridge, Clifford Allbutt Building, Hills Road, Cambridge, CB2 0AH.
Telephone: 01223 762074
General enquiries:


University of Cambridge
Department of Oncology
Lab Director
University of Cambridge
Department of Oncology
Quality Lead
University of Cambridge
Department of Oncology
Lab Manager
University of Cambridge
Department of Oncology
CMDL Administrator