Professor Ben Simons
Professor Ben Simons is pleased to consider applications from prospective PhD students.
We are interested in the role of stem cells in the maintenance of adult tissue. In particular, by drawing of the results of inducible genetic labelling, we have studied the mechanism of epidermal maintenance in mouse. Currently, we are extending these ideas to explore cell fate in human epidermis addressing both normal and malignant tissue. These investigations are pursued in close collaboration with experimentalists in Cambridge.
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E. Clayton, D. P. Doupe, A. M. Klein, D. Winton, B. D. Simons, and P. H. Jones (2007), A single type of progenitor cell maintains the epidermis, Nature 446 , 185. A. M. Klein, D. P. Doupe, P. H. Jones, and B. D. Simons (2007), Kinetics of cell division in epidermal maintenance, Phys. Rev. E. 76, 021910