Professor Carlos Caldas

University of Cambridge

University departments
Department of Oncology
NHS or other affiliations
Honorary Academic Clinical Consultant

Position: Professor
Personal home page:

PubMed journal articles - click here

Professor Carlos Caldas is pleased to consider applications from prospective PhD students.

Research description

BREAST CANCER FUNCTIONAL GENOMICS The molecular taxonomy of breast cancers has revealed a complexity that suggests that different cancers have different cells of origin. The identification and characterisation of these cancer stem cells and their disrupted pathways is one of our research priorities. In parallel we will continue to prospectively validate prognostic and predictive signatures and therapeutic targets with the aim of clinical application.

Research Programme or Virtual Institute
Breast Cancer Virtual Institute
Recent publications:
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Key publications

Naderi A, Teschendorff AE, Beigel J, Cariati M, Ellis IO, Brenton JD, and Caldas C (2007). Bex2 is overexpressed in a subset of primary breast cancers and mediates NGF/NF-kB inhibition of apoptosis in breast cancer cell lines. Cancer Research 67: 6725-6736

Teschendorff AE, Journée M, Absil P-A, Sepulchre R, and Caldas C (2007). Elucidating the altered transcriptional programs in breast cancer using Independent Component Analysis. PLoS Computational Biology, 3(8):e16

Chin S-F, Wang Y, Thorne NP, Teschendorff AE, Pinder SE, Vias M, Naderi A, Roberts I, Barbosa-Morais NL, Garcia MJ, Iyer NG, Kranjac T, Robertson JFR, Aparicio S, Tavaré S, Ellis IO, Brenton JD, and Caldas C (2007). Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers. Oncogene, 26: 1959-1970