Dr Daniel Munoz-Espin

University of Cambridge
Department of Oncology
Hutchison MRC Research Centre

Position: Senior Research Associate
Personal home page: https://www.munoz-espinlab.com
Email:   dm742@cam.ac.uk

PubMed journal articles - click here

Research description

My group works at the interface between cellular senescence, plasticity and the fundamental processes and mechanisms that lie at the origin of cancer. We are also developing novel tools and nanodevices for cancer early diagnosis and therapy.

For people interested in joining my laboratory, please contact me directly (dm742@cam.ac.uk).

Research Programme
Early Detection
Keywords

Lung cancer
Cellular senescence
Cellular plasticity
Cancer stem cells
Diagnosis
Therapy
Nanotechnology

dm742
Recent publications:
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Key publications

A versatile drug delivery system targeting senescent cells.
Muñoz-Espín D*, Rovira M, Galiana I, Giménez C, Lozano-Torres B, Paez-Ribes M, Llanos S, Chaib S, Muñoz M, Ucero AC, Garaulet G, Mulero F, Dann S, VanArsdale T, Shields DJ, Bernardos A, Murguía JR, Martínez-Máñez R, Serrano M*.
EMBO Mol Med. 2018 Jul 16. pii: e9355.

Cellular senescence: from physiology to pathology.
Muñoz-Espín D, Serrano M.
Nat Rev Mol Cell Biol. 2014 Jul;15(7):482-96.

Programmed cell senescence during mammalian embryonic development.
Muñoz-Espín D, Cañamero M, Maraver A, Gómez-López G, Contreras J, Murillo-Cuesta S, Rodríguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M.
Cell. 2013 Nov 21;155(5):1104-18.

- Commentaries on my Cell paper:

Cell biology: the beginning of the end.
Campisi J.
Nature. 2014;505:35-36.

A new development in senescence.
Banito A, Lowe SW.
Cell. 2013;155:977-978.

Developentally programmed senescence.
Baumann K.
Nat Rev Mol Cell Biol. 2013;15:4.

The benefits of aging: cellular senescence in normal development.
Pérez-Garijo A, Steller H.
EMBO J. 2014;33:99-100.