Dr Manav Pathania

University of Cambridge

University departments
Milner Therapeutics Institute
Department of Oncology

Position: Group Leader
Personal home page: https://www.pathanialab.com/
Email:   mp915@cam.ac.uk

PubMed journal articles - click here

Dr Manav Pathania is pleased to consider applications from prospective PhD students.

Research description

Please see https://www.pathanialab.com/ for a description of the research being conducted in the Pathania Lab.

Research Programme or Virtual Institute
Brain Cancer Virtual Institute
Secondary Programme
Fundamental Biology of Cancer
Methods and technologies
Confocal microscopy
DNA sequencing
Gene expression profiling
In vivo modelling
Model organisms
Protein biochemistry
Recombinant protein expression
Tumour type interests
Brain and central nervous system
Recent publications:
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Key publications

Pathania, M. et al. (2017) H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. Cancer Cell 32 (5), 684-700 e9. https://www.ncbi.nlm.nih.gov/pubmed/29107533

Low magnification view of an H3.3K27M tumour that has both diffusely invasive as well as focalised components. Green: GFP, blue: nuclear stain, red: Ki67, a marker of proliferating cells.