Dr Manav Pathania

University of Cambridge

University departments: 
Milner Therapeutics Institute
Department of Oncology

Position: Group Leader
Personal home page: https://www.pathanialab.com/
Email:   mp915@cam.ac.uk

PubMed journal articles - click here

Dr Manav Pathania is pleased to consider applications from prospective PhD students.

Research description: 

Please see https://www.pathanialab.com/ for a description of the research being conducted in the Pathania Lab.

Research Programme or Virtual Institute: 
Brain Cancer Virtual Institute
Secondary Programme: 
Fundamental Biology of Cancer
Methods and technologies: 
Bioinformatics
Confocal microscopy
DNA sequencing
Gene expression profiling
Genomics
Immunohistochemistry
In vivo modelling
Microscopy
Model organisms
PCR
Protein biochemistry
Recombinant protein expression
RNAi
Tumour type interests: 
Brain and central nervous system
mp915
Recent publications:
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Key publications: 

Pathania, M. et al. (2017) H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. Cancer Cell 32 (5), 684-700 e9. https://www.ncbi.nlm.nih.gov/pubmed/29107533

Low magnification view of an H3.3K27M tumour that has both diffusely invasive as well as focalised components. Green: GFP, blue: nuclear stain, red: Ki67, a marker of proliferating cells.