Dr Florian Markowetz
Dr Florian Markowetz is pleased to consider applications from prospective PhD students.
We develop computational approaches for the systems genetics of cancer. To identify drivers of cancer we link genetic data to molecular and cellular phenotypes. Our work combines two complementary directions by (1) analyzing global portraits of cancer and (2) modeling key mechanisms and their response to perturbations.
E.M. Ross and F. Markowetz (2016) OncoNEM: Inferring tumour evolution from single-cell sequencing data. Genome Biology 2016, 17:69
K. Yuan et al (2015) BitPhylogeny: A probabilistic framework for reconstructing intra-tumor phylogenies. Genome Biology, 2015, 16:36
Schwarz et al (2015) Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic reconstruction. PLoS Medicine, 2015 Feb 24;12(2):e1001789.