Dr Kristian Franze


University departments
Department of Physiology, Development and Neuroscience

Position: Lecturer
Personal home page: http://www.pdn.cam.ac.uk/franze

PubMed journal articles - click here

Dr Kristian Franze is pleased to consider applications from prospective PhD students.

Research description

We are interested how mechanical signals contribute to the physiology and pathology of tissues and cells, focusing on the central nervous system. For more information, please visit www.pdn.cam.ac.uk/franze

Research Programme or Virtual Institute
Early Cancer Institute
Methods and technologies
Atomic force microscopy
Calcium imaging
Cell culture
Confocal microscopy
Fluorescence microscopy
Imaging
Immunohistochemistry
In vivo modelling
Microscopy
Model organisms
Other
Tumour type interests
Brain and central nervous system
Keywords
mechanobiology
mechanosensitivity
mechanotransduction
atomic force microscopy
traction force microscopy
compliant culture substrates
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Recent publications:
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Key publications

Pagliara S*, Franze K*, McClain CR, Wylde G, Fisher CL, Franklin RJM, Kabla AJ, Keyser UF, Chalut KJ: Auxetic nuclei in embryonic stem cells exiting pluripotency. Nature Materials 13:638-644 (2014)

Moshayedi P, Ng G, Kwok JC, Yeo GSH, Bryant C, Fawcett J, Franze K*, Guck J: The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system. Biomaterials 35(13):3919-3925 (2014)

Franze K: The mechanical control of nervous system development. Development 140:3069-3077 (2013)

Hardie RC and Franze K: Photomechanical responses in Drosophila photoreceptors. Science 338(6104):260-263 (2012)