Dr John Lizhe Zhuang

University of Cambridge

University departments
MRC Cancer Unit
University institutes
Hutchison MRC Research Centre

Position: Research Associate
Personal home page:
Email:   Public email address:  LZ377@MRC-CU.cam.ac.uk

PubMed journal articles - click here

Research description

My research focus on 1) how immune complexity evolves in Oesophageal adenocarcinoma and its precancerous lesion, Barrett's oesophagus. Using several advanced multiplex imaging technologies and novel computational algorithm Sparse Subspace Coding, we aim to decipher which are the key immune cell populations that involved in the progression of cancer; 2) what and how intrinsic genetic and extrinsic environmental factors initiate and promote the malignant progression from Barrett's oesophagus to Oesophageal adenocarcinoma. We have established multiple lines of in vitro experimental models to answer these questions.

Research Programme
Early Detection
Methods and technologies
Bioinformatics
Cell culture
Fluorescence microscopy
Imaging
Immunohistochemistry
In vivo modelling
Tumour type interests
Oesophagus
lz377
Recent publications:
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