Dr Martin Graves

Cambridge University Hospitals NHS Foundation Trust

University departments
Department of Radiology
NHS or other affiliations
Consultant Clinical Scientist

Position: Consultant Clinical Scientist
Personal home page: http://radiology.medschl.cam.ac.uk/about-us/departmental-staff/research-staff/dr-martin-j-graves/

PubMed journal articles - click here

Research description

The development of MRI acquisition and analysis methods in oncology. We have developed and applied advanced methods for dynamic contrast enhanced (DCE) and diffusion weighted imaging (DWI) techniques in human subjects using both 1.5T and 3T MRI systems. We also support the development of new multi-nuclear imaging techniques including 23Na and hyperpolarised 13C. In the near future we will be translating our methods to PET/MR.

Research Programme
Advanced Cancer Imaging
Methods and technologies
Magnetic Resonance Imaging (MRI)
mjg40
Recent publications:
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Key publications

C. J. Daniels, M. A. McLean, R. F. Schulte, F. J. Robb, A. B. Gill, N. McGlashan, M. J. Graves, M. Schwaiger, D. J. Lomas, K. M. Brindle, and F. A. Gallagher. A comparison of quantitative methods for clinical imaging with hyperpolarized 13c-pyruvate. NMR in Biomedicine, 2016.
T. E. Wallace, A. J. Patterson, O. Abeyakoon, R. Bedair, R. Manavaki, M. A. McLean, J. P. O’Connor, M. J. Graves, and F. J. Gilbert. Detecting gas-induced vasomotor changes via blood oxygenation level-dependent contrast in healthy breast parenchyma and breast carcinoma. J Magn Reson Imaging, 2016.
A. J. Patterson, A. N. Priest, D. J. Bowden, T. E. Wallace, I. Patterson, M. J. Graves, and D. J. Lomas. Quantitative bold imaging at 3T: Temporal changes in hepatocellular carcinoma and fibrosis following oxygen challenge. J Magn Reson Imaging, 2016.
R. Bedair, M. J. Graves, A. J. Patterson, M. A. McLean, R. Manavaki, T. Wallace, S. Reid, I. Mendichovszky, J. Griffiths, and F. J. Gilbert. Effect of radiofrequency transmit field correction on quantitative dynamic contrast-enhanced MR imaging of the breast at 3.0 T. Radiology, 2015.
A. B. Gill, G. Anandappa, A. J. Patterson, A. N. Priest, M. J. Graves, T. Janowitz, D. I. Jodrell, T. Eisen, and D. J. Lomas. The use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data. Magn Reson Imaging, 33(2):246–251, 2015.
A. B. Gill, R. T. Black, D. J. Bowden, A. N. Priest, M. J. Graves, and D. J. Lomas. An investigation into the effects of temporal resolution on hepatic dynamic contrast-enhanced MRI in volunteers and in patients with hepatocellular carcinoma. Phys Med Biol, 59(12):3187–3200, 2014.
T. Barrett, A. B. Gill, M. Y. Kataoka, A. N. Priest, I. Joubert, M. A. McLean, M. J. Graves, S. Stearn, D. J. Lomas, J. R. Griffiths, D. Neal, V. J. Gnanapragasam, and E. Sala. Dce and DW MRI in monitoring response to androgen deprivation therapy in patients with prostate cancer: a feasibility study. Magn Reson Med, 67(3):778–785, 2012.
M. O. Leach, B. Morgan, P. S. Tofts, D. L. Buckley, W. Huang, M. A. Horsfield, T. L. Chenevert, D. J. Collins, A. Jackson, D. Lomas, B. Whitcher, L. Clarke, R. Plummer, I. Judson, R. Jones, R. Alonzi, T. Brunner, D. M. Koh, P. Murphy, J. C. Waterton, G. Parker, M. J. Graves, T. W. J. Scheenen, T. W.
Redpath, M. Orton, G. Karczmar, H. Huisman, J. Barentsz, A. Padhani, and E. C. M. C. I. Network. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. European Radiology, 22(7):1451–1464, 2012.
E. Sala, M. Y. Kataoka, A. N. Priest, A. B. Gill, M. A. McLean, I. Joubert, M. J. Graves, R. A. Crawford, M. Jimenez-Linan, H. M. Earl, C. Hodgkin, J. R. Griffiths, D. J. Lomas, and J. D. Brenton. Advanced ovarian cancer: multiparametric MR imaging demonstrates response- and metastasis-specific effects.
Radiology, 263(1):149–159, 2012.