Dr Matthew Murray

Cambridge University Hospitals NHS Foundation Trust
University of Cambridge
Department of Pathology
Department of Paediatrics

Position: Lecturer
Personal home page: https://www.researchgate.net/profile/Matthew_Murray

PubMed journal articles - click here

Dr Matthew Murray is pleased to consider applications from prospective PhD students.

Research description

Our lab is undertaking a national Children's Cancer and Leukaemia Group (CCLG) approved study, investigating non-coding RNAs, including microRNAs (miR-), in malignant germ cell tumours and other childhood cancers. Our lab has a particular interest in circulating microRNA biomarkers, with a particular focus on germ cell tumours.

Research Programme
Paediatric Cancers
Methods and technologies
Bioinformatics
Cell culture
Clinical trials
Gene expression profiling
Genomics
Microarray
PCR
RNAi
Tumour type interests
Brain and central nervous system
Ovary
Testis
Other

Key publications

1. Murray MJ, Huddart RA, Coleman N (2016) The present and future of serum diagnostic tests for testicular malignant germ cell tumours. Nature Reviews Urology, In Press.

2. Shaikh F, Murray MJ, et al (2016) Paediatric extracranial germ cell tumours. Lancet Oncology, 17:e149-62.

3. Murray MJ, Bell E, et al (2016) A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ cell tumours. British Journal of Cancer, 114:151-62.

4. Murray MJ, Bartels U, et al (2015) Consensus in the management of intracranial germ-cell tumours. Lancet Oncology, 16:e470-7.

5. Olson TA, Murray MJ, et al (2015) Pediatric and Adolescent Extracranial Germ Cell Tumors - The Road to Collaboration. Journal of Clinical Oncology, 33:3018-28.

6. Murray MJ, Raby KL, et al (2015) Solid tumors of childhood display specific serum microRNA profiles. Cancer Epidemiology, Biomarkers & Prevention, 24:350-60.

7. Frazier AL, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray MJ, et al (2015) Revised Risk Classification for Pediatric Extracranial Germ Cell Tumors Based on 25 Years of Clinical Trial Data from the United Kingdom and United States. Journal of Clinical Oncology, 33:195-201.

8. Murray MJ, Bailey S, et al (2014) Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma. Oncogenesis, 3:e87.

9. Murray MJ, Saini HK, et al (2013) LIN28 expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Research, 73:4872-84.

10. Gillis AJM, Rijlaarsdam MA, Eini R, Dorssers LCJ, Biermann K, Murray MJ, et al (2013) Targeted Serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle. Molecular Oncology, 7:1083-1092.

11. Murray MJ, Coleman N (2012) Testicular cancer: A new generation of biomarkers for malignant germ cell tumours. Nature Reviews Urology, 9:298-300.

12. Murray MJ, Halsall D, et al (2011) Identification of MicroRNAs from the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. American Journal of Clinical Pathology, 135:119-125.

13. Palmer RD*, Murray MJ*, et al (2010) Malignant Germ Cell Tumors Display Common MicroRNA Profiles Resulting in Global Changes in Expression of Messenger RNA Targets. Cancer Research, 70:2911-23. *joint first authors