Mr Oscar Baldwin

University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

University departments
Cancer Research UK Cambridge Institute
University institutes
CRUK Cambridge Institute
NHS or other affiliations
Cambridge University Hospitals NHS Trust

Position: PhD student
Personal home page:

PubMed journal articles - click here

Research description

My research focuses on choroid plexus carcinoma (CPC), an extremely rare paediatric brain cancer. Currently, there is a lack of understanding as to how this tumour type begins in utero  and how it develops within the brain. Furthermore, there is a lack of clinical consensus on best practice for its treatment, due to a lack of understanding of the disease and its rarity. My work aims at understanding the events that allow the normal developing choroid plexus epithelium to transform into a tumour, how it maintains its tumourigenicity, and characterising how the tumour changes over time. This builds on previous work within the Gilbertson group in both the UK under Cancer Research UK and at St. Jude's Children's Research Hospital in the USA.

Research Programme or Virtual Institute
Paediatric Cancer
Secondary Programme
Cancer Immunology
Methods and technologies
Cell culture
Confocal microscopy
DNA sequencing
Gene expression profiling
In vivo modelling
Model organisms
Protein biochemistry
Protein purification
Statistical analysis
Tumour type interests
Brain and central nervous system
choroid plexus carcinoma
choroid plexus cancer
Li-Fraumeni syndrome
paediatric cancer
brain cancer
TP53 deletion
Recent publications:
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