My research focuses on choroid plexus carcinoma (CPC), an extremely rare paediatric brain cancer. Currently, there is a lack of understanding as to how this tumour type begins in utero  and how it develops within the brain. Furthermore, there is a lack of clinical consensus on best practice for its treatment, due to a lack of understanding of the disease and its rarity. My work aims at understanding the events that allow the normal developing choroid plexus epithelium to transform into a tumour, how it maintains its tumourigenicity, and characterising how the tumour changes over time. This builds on previous work within the Gilbertson group in both the UK under Cancer Research UK and at St. Jude's Children's Research Hospital in the USA.