Dr Siddhartha Kar

University of Cambridge
Department of Public Health and Primary Care

Position: Homerton College Junior Research Fellow in Clinical Medicine
Personal home page: https://scholar.google.co.in/citations?user=WAXlOQ0AAAAJ&hl=en

PubMed journal articles - click here

Research description

I studied medicine at the Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospital in Pune, India (2009).

I also hold a master of public health degree (2012) from the University of Texas at Houston in the United States and a PhD (2017) in cancer genetics and epidemiology from the University of Cambridge in the United Kingdom, where I was a Gates Scholar.

My current research investigates the shared genetic origins of different cancers, regardless of the part of the human body where they eventually manifest.

Cancer is a disease of the genome and I use these shared genetic origins as starting points for the identification of functional interactions between the inherited genome and the tumour genome.

My focus on the shared genetic origins of cancers afflicting different organs automatically provides a unique opportunity to replicate across cancer types and therefore build confidence that the identified interactions represent important mechanisms driving these cancers.

I also study the overlapping genetic basis of cancers and their risk factors — particularly non-cancer conditions, such as endometriosis, that increase the risk of subsequently developing cancers, such as ovarian cancer.

The overarching goal of my work is to better understand cancer and its biology — this is essentially an endeavour in basic science informed by population-scale data from the largest international networks of genetic association studies for cancer.

An unwavering commitment to this goal has the potential to inform and improve cancer prevention and treatment.

Finally, I have an interest in scientific and healthcare policy in India and have written on this for The Lancet (2017) and in Nature (2012).

Research Programme
Ovarian Cancer
Recent publications:
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