Dr Thankamma Ajithkumar

Cambridge University Hospitals NHS Foundation Trust

University departments
Department of Oncology
NHS or other affiliations
Consultant Clinical Oncologist, Cambridge University Hospital NHS Trust. Associate Lecturer, University of Cambridge

Position: Scientific Officer
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PubMed journal articles - click here

Dr Thankamma Ajithkumar is pleased to consider applications from prospective PhD students.

Research description

His research interest is to optimize the combination of radiotherapy with novel agents in paediatric brain tumours and hepato-pancreatico-biliary tumours to improve clinical outcomes.

He is the Chief Investigator of PORTICO-SABR trial which evaluates the feasibility and safety of delivering stereotactic ablative radiotherapy (SABR) followed by immediate surgery in operable pancreatic adenocarcioma. This study will also explore the effects of SABR on the tumour immune microenvironment and putative biomarkers of the DNA damage response (DDR).

Dr Ajithkumar is the Chair of the European Society of Paediatric Oncology (SIOPE) Brain Tumour Radiotherapy group. He is the principal investigator for the international Pediatric Normal Tissue Effects in the Clinic (PENTEC) Re-irradiation working group. He is also the radiotherapy lead for the CCLG CNS GCT subgroup and the radiotherapy research lead for the Cancer Research Network: Eastern.

He is the lead editor of the text books: Specialist training in Oncology (Elsevier), Oxford Desk Reference in Oncology, and Oxford Case histories in Oncology.

Research Programme
Neuro-Oncology
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Recent publications:
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Key publications

1. Hoeben BA, Carrie C, Timmermann B, Mandeville HC, Gandola L, Dieckmann K, Ramos Albiac M, Magelssen H, Lassen-Ramshad Y, Ondrová B, Ajithkumar T et al. Management of vertebral radiotherapy dose in paediatric patients with cancer: consensus recommendations from the SIOPE radiotherapy working group. Lancet Oncol. 2019;20(3):e155-e166.
2. Ajithkumar T, Kortmann RD. "Indeed, Cure is Not Enough" - A Reflection on Paediatric Radiation Oncology. Clin Oncol (R Coll Radiol). 2019 ;31(3):135-138.

3. Ajithkumar T, Horan G, Padovani L, et al. SIOPE BTG Radiotherapy Group. SIOPE - Brain tumor group consensus guideline on craniospinal target volume delineation for high-precision radiotherapy. Radiother Oncol. 2018;128(2):192-197.