Mr Thierry Lefebvre
Position: PhD student
Personal home page:
https://www.bohndieklab.org/people/entry/thierry-lefebvre/
Email:
thierry.lefebvre@cruk.cam.ac.uk
PubMed journal articles - click here
Radiotherapy is often prescribed in oncology clinics to treat solid tumours and to limit the development and the propagation of cancer cells. The lack of oxygenation seen in some tumour regions under chaotic and unrestricted cellular growth constitute a great barrier to the efficacy of these treatments. Thus, we aim to understand radiotherapy response and resistance using advanced multimodal imaging to study the dynamic nature of hypoxia.
Symplectic Elements feed provided by Research Information, University of Cambridge
Lefebvre TL, Ueno Y, Dohan A, Chatterjee A, Vallières M, Winter-Reinhold E, Saif S, Levesque IR, Zeng XZ, Forghani R, Seuntjens J, Soyer P, Savadjiev P, Reinhold C. Development and Validation of Multiparametric MRI-based Radiomics Models for Preoperative Risk Stratification of Endometrial Cancer. Radiology. 2022 Nov;305(2):375-386. doi: 10.1148/radiol.212873.
Goodburn R, Philippens MEP, Lefebvre TL, Khalifa A, Bruijnen T, Freedman JN, Waddington DEJ, Younus E, Aliotta E, Meliado G, Stanescu T, Bano W, Fatemi-Ardekani A, Wetscherek A, Oelfkw U, van den Berg N, Mason RP, van Houdt PJ, Balter JM, Gurney-Champion OJ. The future of MRI in Radiation Therapy: Challenges and Opportunities for the MR Community. Magnetic and Resonance in Medicine. 2022 Dec;88(6):2592-2608. doi: 10.1002/mrm.29450.
Lefebvre TL, Ozan C, Bhatnagar SR, Ueno Y, Saif S, Winter-Reinhold E, Dohan A, Soyer P, Forghani R, Siddiqi K, Seuntjens J, Reinhold C, Savadjiev P. Predicting histopathology markers of endometrial carcinoma using a novel quantitative image analysis approach based on spherical harmonics in multiparametric MRI. Diagnostic and Interventional Imaging. 2023 Mar;104(3):142-152. doi: 10.1016/j.diii.2022.10.007.
Brown EL*, Lefebvre TL*, Sweeney PW*, Stolz B, Grohl J, Hacker L, Huang Z, Harrington H, Byrne H, Bohndiek SE. Quantification of vascular networks in photoacoustic mesoscopy. Photoacoustics. 2022 Apr 20;26:100357. doi: 10.1016/j.pacs.2022.100357.
Lefebvre TL, Brown EL, Hacker L, Else T, Oraiopoulou ME, Tomaszewski MR, Jena R, Bohndiek SE. The Potential of Photoacoustic Imaging in Radiation Oncology. Frontiers in Oncology. 2022 Mar 3;12:803777. doi: 10.3389/fonc.2022.803777.
