Dr Yan Yan Shery Huang

University of Cambridge

University departments
Department of Engineering

Position: Lecturer
Personal home page: http://www.eng.cam.ac.uk/profiles/yysh2

PubMed journal articles - click here

Dr Yan Yan Shery Huang is pleased to consider applications from prospective PhD students.

Research description

My research group is interested in designing and developing biomimetic organ-on-chips for high-throughput drug testing. Living tissues are intricate ensembles of multiple cell types embedded in a complex, but well-defined extracellular matrix (ECM) of topographical and adhesive features ranging from nanometres to micrometres. Cell ladened ECMs act like units of reaction centres and information hubs. Corporation between these small units lead to a hierarchical structure (i.e. a human body) achieving homeostasis (balance). We combine nanotechnology and new material fabrication techniques to construct the defined biochemical and physical inputs of an ECM scaffold, and to recapitulate the key attributes of a 'niche' unit. Our research is highly multi-disciplinary in nature, crossing fields of engineering, biology, chemistry, polymer physics and computer science. We aim to translate our scientific findings into exploring a new generation of tissue engineering constructs for personalised therapy, at affordable costs; and to provide new solutions for disease monitoring, drug testing, and better patient healthcare.

Research Programme
Early Detection
Keywords
Biomimetic Niche Model
Biofabrication
Organ-on-chips.
yysh2
Recent publications:
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