International experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included thirty-five participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from PhD students to senior professors. Data from a variety of model systems as well as from clinical gene therapy trials were discussed alongside strategies for data analysis and sharing, as well as challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.
The workshop was co-organised by Programme members Dr David Kent and Dr Elisa Laurenti and collaborators Dr Ingmar Glauche (TU Dresden), Dr Anne-Marie Lyne (Institute Curie), and Dr Leila Perié (Institute Curie). This workshop summary is an extract from the full workshop report published in Experimental Haematology.
