Search results
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Dr Catherine Lindon
... role of substrate proteolysis in the precisely coordinated events giving rise to two daughter cells at the end of mitosis. The Aurora ...
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Dr Athena Matakidou
... modify the mouse renal apithelium and replicate the genetic events observed in human renal cell carcinoma. The development of reproducible ...
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Dr Mariann Bienz
... cell compartment. Our aim is to understand the molecular events underlying Wnt signal transduction. We focus on positively-acting ...
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Dr Dario Bressan
... for the spatial and temporal control of biological events in vivo. Specifically, I am using photochemically caged ligands and ...
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Dr Frank McCaughan
My research is focused on understanding the early driver events that are critical to the development of squamous lung cancer (SQC) and ...
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Professor Gillian Murphy
... by trafficking which allows specific localisation in events such as cell invasion. The identification of the importance of specific ...
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Dr James Nathan
Cellular mechanisms of oxygen and metabolite sensing: ...
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Dr James Rudd
... arteries as a predictor of plaque rupture and clinical events. Additionally, I use non-invasive imaging methods such as PET, MRI and ...
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Dr Marisa Segal
... morphogenesis in S. cerevisiae we have focused on the events that determine SPB asymmetry or spindle polarity, i.e. the mechanisms ...
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Mr Oscar Baldwin
... disease and its rarity. My work aims at understanding the events that allow the normal developing choroid plexus epithelium to transform ...
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Dr David Gilligan
David Gilligan is a Consultant Clinical Oncologist at Addenbrooke's and Papworth Hospitals in Cambridge. He is the Clinical Lead for Acute Oncology at Addenbrooke's. He trained in pre clinical medicine at the University of Edinburgh and clinical...
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Mr David Thurtle
Radiological assessment of prostatic osseous metastases. Robotic-assisted laparoscopic prostatectomy. Early detection of prostate cancer. Risk Prediction in prostate cancer
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Dr Roisin Owens
Our group works on integrating biological models with electronic devices to generate systems that can be predictive of real biological systems, for drug discovery and therapeutics. We combine expertise in a wide range of disciplines including...
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Mr Thierry Lefebvre
Radiotherapy is often prescribed in oncology clinics to treat solid tumours and to limit the development and the propagation of cancer cells. The lack of oxygenation seen in some tumour regions under chaotic and unrestricted cellular growth constitute a...
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Professor Walid Khaled
My laboratory works on defining the early cellular and molecular events that drive tumour initiation and development. In particular, we focus on how the cell of origin affects the differentiation trajectory of nascent tumour cells and dictates changes...
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Dr Andrew Murray
Our interest lies in the control of mitochondrial respiration and energy metabolism. We are interested in the metabolic response to dietary manipulation and alterations in oxygen supply, including the matching of oxygen demand and supply. We study this...
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Dr Alan Wright
(tbc)
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Mrs Amanda Walker
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Mrs Anne Omaolain
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Dr Christopher Jones
My research focuses on improving the radiation response and post-radiation monitoring of oesophageal cancers, with a particular focus on oesophageal adenocarcinoma. I am also interested in the study of radiotherapy-related genomic evolution.
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Professor Charlotte Coles
Charlotte Coles is Professor of Breast Cancer Clinical Oncology and NIHR Research Professor at the CRUK Cambridge Centre. Her research aims are to provide breast cancer patients with the best chance of cure with least side effects by personalising...
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Mrs Debbie Read
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Dr Dominick McIntyre
Head of the CRUK CI Imaging Core Facility, specialising in preclinical MRI and image databases, and running a team supporting research in clinical & preclinical MR, BLI/FLI, CT and radionuclide imaging, and ultrasound.
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Dr Elizabeth Soilleux
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Dr Felicia Ng
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Professor Julie Ahringer
We investigate the functions chromatin regulatory complexes implicated in human disease using the C. elegans model system. These include the histone deacetylase complex NuRD, the Retinoblastoma complex DRM, and a TIP60 histone acetyltransferase complex....
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Mr Julius Christopher Baeck
I am a Wellcome Trust-funded PhD student in Klaus Okkenhaug's lab, Department of Pathology, University of Cambridge. My research focuses on the role of the lipid signalling kinase PI3K δ in B cell homoeostasis. I am particularly...
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Dr Julia Carmona-Bozo
My study focuses on imaging Breast cancer by using PET-MRI
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Dr Julian Sale
My lab is interested in the mechanisms that alleviate arrested DNA replication and the impact their loss has on mutagenesis and on the maintenance of epigenetic memory through the recycling of histones during replication. Replication can be arrested by...
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Dr Julia Wilson
Cambridge Cancer Centre Executive Committee, Associate Director for Genetics and Genomics
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Miss Julia Knight
Various projects for Lung Cancer research. Main project working on is Mesobank, preforming the quality control for solid tissue collected.
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Dr Julia Moreno-Vicente
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Miss Júlia Ponte
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Dr Juliane Perner
Application of computational biology approaches to integrate different types of 'omics'-data with a focus on improving our understanding of the molecular biology of Esophageal cancer and Barrett's esophagus.
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Dr Julie Stockis
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Professor Eric Miska
... of biology. We will concentrate on basic questions on how microRNAs control gene expression. Our approach is multi-facetted, combining ...
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Miss Marta Ferraresso
Understanding the role of underexpressed microRNAs in malignant germ cell tumours ...
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Professor Matthew Murray
... approved study, investigating non-coding RNAs, including microRNAs (miR-), in malignant germ cell tumours and other childhood cancers. ...
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Mr Amit Roshan
... research focus is currently exploring the utility of circulating tumour DNA (ctDNA) in early melanoma, and progressing our ...
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Dr Emma Beddowes
Investigating the development and application of circulating free nucleic acids to breast cancer research. ...
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Dr Fazlur Rahman Talukdar
... a translational research initiative focused on developing circulating tumour DNA (ctDNA) based biomarkers derived from minimally invasive ...
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Dr Laura Blackburn
... into healthcare. We have a particular interest in circulating tumour DNA technologies and their potential in terms of cancer ... can be viewed here: http://www.phgfoundation.org/research/circulating-tumour-DNA. We found that while some patients were benefiting ...
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Dr Lucy Faulkner
My research looks at epigenetic changes in circulating tumour DNA (ctDNA) for early detection, active surveillence and ...
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Dr Meiling Gao
Circulating biomarkers in breast cancer
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Dr Nitzan Rosenfeld
... of molecular and genomic technologies. Our focus is on circulating tumour DNA (ctDNA) as a noninvasive modality to assess evolution of ...
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Mr Richard Mair
My research is focused on the interaction between the microenvironment and genome and how this comes to define brain tumours. I am using novel and ...
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Mr Samuel White
... formalin-fixed paraffin embedded tissue (FFPE) as well as circulating tumour DNA and Germ line DNA from blood samples and processed blood ...
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Dr Andrew Pierce
DNA damage and repair, oncology clinical biomarkers
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Dr Anna Piskorz
... ovarian cancer (HGSOC). I work on identification of genomic biomarkers that could be applied in clinic as diagnostic, prognostic and predictive biomarkers, helping in better patient stratification, earlier disease ...
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Dr Pippa Corrie
... studies focusing on angiogenesis predictive and prognostic biomarkers. Locally, am collaborating with Ultan McDermott, studying gene ...
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Dr Dorentina Bexheti
... methods for the analysis small molecules and metabolites/biomarkers in biological matrices, cancer tissues and cells, using different ...
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Professor Evis Sala
... clinical development and validation of functional imaging biomarkers to rapidly evaluate treatment response using physiologic and ...
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Professor Ferdia Gallagher
... humans. The focus of this work is to develop new molecular biomarkers for the detection of cancer as well as methods to assess early ...
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Professor Fiona Gilbert
... I am keen to develop predictive and surrogate response biomarkers using these functional imaging tools with the aim of improved ... new oncological radiotracers which may be valuable as biomarkers for patient care or in drug development. ...
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Dr Gaia Schiavon
... resistance mechanisms in ER positive breast cancers - Novel biomarkers and study designs in ‘window of opportunity’ ...
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Dr Ali Amin Al Olama
... has focused on discovery of genetic risk factors of prostate cancer through genome-wide association studies and fine-mapping. I am a core member of an international consortium PRACTICAL (Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the ...
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Dr Andreas Bender
... large amounts of chemical or biological data related to cancer drug discovery you are very welcome to contact me to see in which way I ...
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Dr Alejandra Bruna
... aimed to study the effects of the TGF-beta pathway in breast cancer stem cell (BCSC) regulation. To define a role of the TGF-beta pathway in ... of human BCSCs, we have analyzed a panel of breast cancer cell lines that represent the molecular heterogeneity present in primary ...
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Professor Antonis Antoniou
... component; - the identification and characterisation of cancer risks for genetically susceptible individuals, such as those carrying ...
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Dr Alison Dunning
Work in the Centre for Cancer Genetic Epidemiology "wet lab" involves running very high throughput ... (NGS) studies. We search for genetic risk factors for both cancer susceptibility and treatment-response. In this we collaborate closely ... consortia for breast, ovarian, endometrial and prostate cancer association studies: BCAC http://bcac.ccge.medschl.cam.ac.uk, CIMBA ...
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Dr Ashray Gunjur
... broadly interested in immuno-oncology and the link between cancer and the gut microbiome, and am undertaking a PhD supervised by Dr David ... between gut microbiota and outcomes in patients with rare cancer types. ...
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Dr Ahsan MEMON
... this holographic system was deployed to the study of cancer and stem cell shape regulation and the role of effective membrane ...
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Professor Alan Warren
... how defects in this process cause bone marrow failure and cancer predisposition. Assembly of the two subunits of the ribosome, containing ... it is also important for oncogenesis: a novel class of human cancer predisposition disorder has recently emerged that is caused by mutations ...
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Dr Alexey Larionov
Hormonal treatment and resistance in Breast cancer Heritable cancer predisposition NGS data analysis ...
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Dr Adrian Ionescu
... up a strong track record with international recognition in these research areas, with 50 publications and two books to date. With some of these publications I have helped shape the new interdisciplinary field of ...
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Professor Andrew Flewitt
... thin film piezoelectrics. There are two applications of these. Surface acoustic wave (SAW) devices can be used to make microfluidic ...
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Dr Alasdair Russell
... model systems in a pre-clinical setting. Further, we use these novel models in a range of pre-clinical trials to advance our ...
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Mr Angelos Kolias
... and evaluation of PET-guided surgery for pituitary adenomas. These are collaborative projects with Mr Richard Mannion (Clinical Lead for ...
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Professor Anna Philpott
... a disease of differentiation. Ultimately, our studies on these fundamental mechanisms that co-ordinate proliferation and differentiation ...
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Professor Anthony Davenport
... imaging using positron emission tomography, to determine how these are altered with disease. Major interests are the role of endothelin-1 in ...
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Dr Alex Cagan
... our own bodies are constantly acquiring mutations. Some of these mutations may influence cellular phenotypes, such as growth, resulting in ... Over time our bodies become a patchwork of clones. These processes drive cancer progression and may contribute to ageing. Due to ...
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Professor Ben Simons
... epidermal maintenance in mouse. Currently, we are extending these ideas to explore cell fate in human epidermis addressing both normal and malignant tissue. These investigations are pursued in close collaboration with experimentalists ...
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Dr Basma Greef
... of hypoxia response pathways in renal cancer and how these can be harnessed to develop new treatments. My other interests include ...
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Professor Adrian Liston
We are focussed on understanding the biology of regulatory T cells within the ...
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Miss Amara Cañizares
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Dr Kerstin Meyer
... analysis of predisposition loci: My experiments are aimed at understanding the mechanisms by which breast cancer risk loci ...
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Dr Misha Kapushesky
... a universal ecosystem for bioinformatics development, aimed to reduce the chaotic clutter of inefficiency and incompatibility in ...
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Dr Nicholas Walton
... currently aiding in their search for new techniques aimed at the treatment of breast cancer. ...
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Professor Rahul Roychoudhuri
... providing targets for development of new therapies aimed at reversing dysfunctional immune responses in cancer. ...
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Dr Shangqi Gao
... the understanding and treatment of ovarian cancer. It is aimed to integrate and analyse diverse data types, including radiological ...
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Dr Sujath Abbas
... I developed a cost-effective DNA sequencing method (mutREAD) aimed for screening of mutational signatures using FFPE DNA, envisioning its ...
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Dr Andre Neves
... response to cancer therapy. Currently, I'm planning a first-in-human clinical trial of a novel cell death imaging agent, C2Am. This ...
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Dr Bristi Basu
... Phase I, II and III clinical trials, including first-in-human and first-in-class studies. My tumour site-specific focus is in ...
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Professor Tim Eisen
... where I am currently responsible for oncology trials from first in man to Phase II. ...
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Dr Elisa Laurenti
... As perturbation of HSC regulatory networks drives the first steps of leukaemia, knowledge of HSC specific molecular responses will ...
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Dr Kelly Holmes
... CRUK Cambridge Centre Imaging Programme Manager. Kelly has a first class degree in Biochemistry with a year in industry. She completed her ...
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Professor Duncan Jodrell
... therapies and novel therapeutic combinations, including first into man (phase I) and associated studies. My research goal is to ...
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Dr Lori Passmore
... of translation to control gene expression, and is the first step in mRNA turnover. The major deadenylase activities are found within ...
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Dr David Adams
... data for over 200 genetically modified mouse lines per year to gain a better understanding of mammalian gene function. ...
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Dr Daniel Hodson
Pathogenesis of Germinal Centre Derived B Cell Lymphomas. Many of the commonest human lymphomas (including follicular, diffuse large B cell and Burkitt lymphomas) develop from a specific stage of B lymphocyte differentiation termed the Germinal Centre. ...
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Dr Joanna Baxter
The Cambridge Blood and Stem Cell Biobank is a facility of over 6000 viable and nucleic acid samples, the majority from patients with haematological malignancy and clonal blood cell disorders; and the remainder, around 20%, from normal individuals,...
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Mrs Eva Serrao
Despite medical advances, pancreatic cancer still has a 5-year survival rate of less than 6%. The ideal way to improve this is to ...
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Dr Hayley Woffendin
After many years working as a postdoctoral research scientist (Molecular Biologist) within the University and Wellcome Trust Sanger Institute, I have been Scientific Administrator and Graduate Student Administrator with the Department of Oncology Since...
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Dr Hannah Harrison
Since moving into public health research around 5 years, Hannah has been involved in projects investigating risk-stratification for kidney cancer screening and follow-up. Her most rencet project, funded by CRUK, is investigating multifactorial models...
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Dr Inigo Martincorena
My research focuses on understanding cancer progression as a result of somatic mutation and selection. Over the past few years, systematic sequencing of tumours has revolutionised our understanding of the genetics of cancer. This has revealed that most...
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Dr Adrien Hallou
... approaches of biological systems during my MPhil and PhD in Biophysics at the University of Cambridge. I am now a Research Fellow at ...
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Dr Amos Burke
... and currently co-supervises a Clinical and a basic science PhD student. At a national level Dr Burke is the National Institute for Health ...
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Miss Annalisa Occhipinti
I am a Mathematician and I am doing a PhD in bioinformatics at the University if Cambridge. I am currently working on ...
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Dr Cedric Ghevaert
... the Royal College of Pathologists in 2005. He obtained his PhD in 2008 studying novel antibodies for the treatment of bleeding in neonates ...
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Ms Ceilidh Welsh
I am a PhD student working with Cancer Research UK RadNet Cambridge Radiation ...
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Dr Danish Mazhar
... and Charing Cross Hospitals in London. He was awarded a PhD by Imperial College London for his research in Prostate Cancer. He has also ...
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Dr Emmanuel Huguet
... undergraduate medical students. He subsequently undertook a PhD in cancer molecular biology at Oxford University in the laboratories of the ...
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Professor Eamonn Maher
... and non-clinician scientists and had supervised more than 25 PhD or MD students to completion. Current research in Eamonn?s group relates to ...